Bionte Nutrition, 43204 Reus, Spain.
Toxins (Basel). 2024 Oct 10;16(10):434. doi: 10.3390/toxins16100434.
Mycotoxins are a major threat to animal and human health, as well as to the global feed supply chain. Among them, aflatoxins, fumonisins, zearalenone, T-2 toxins, deoxynivalenol, and Alternaria toxins are the most common mycotoxins found in animal feed, with genotoxic, cytotoxic, carcinogenic, and mutagenic effects that concern the animal industry. The chronic negative effects of mycotoxins on animal health and production and the negative economic impact on the livestock industry make it crucial to develop and implement solutions to mitigate mycotoxins. In this review, we summarize the current knowledge of the mycotoxicosis effect in livestock animals as a result of their contaminated diet. In addition, we discuss the potential of five promising phytogenics (curcumin, silymarin, grape pomace, olive pomace, and orange peel extracts) with demonstrated positive effects on animal performance and health, to present them as potential anti-mycotoxin solutions. We describe the composition and the main promising characteristics of these bioactive compounds that can exert beneficial effects on animal health and performance, and how these phytogenic feed additives can help to alleviate mycotoxins' deleterious effects.
真菌毒素是动物和人类健康以及全球饲料供应链的主要威胁。其中，黄曲霉毒素、伏马菌素、玉米赤霉烯酮、T-2 毒素、脱氧雪腐镰刀菌烯醇和交链孢菌毒素是动物饲料中最常见的真菌毒素，具有遗传毒性、细胞毒性、致癌性和致突变性，引起动物产业关注。真菌毒素对动物健康和生产的慢性负面影响以及对畜牧业的负面经济影响，使得开发和实施减轻真菌毒素的解决方案至关重要。在这篇综述中，我们总结了由于饮食受到污染，动物发生真菌毒素中毒的现有知识。此外，我们讨论了五种有前途的植物提取物（姜黄素、水飞蓟素、葡萄渣、橄榄渣和橙皮提取物）的潜在应用，这些植物提取物已被证明对动物性能和健康具有积极影响，可以将其作为潜在的抗真菌毒素解决方案。我们描述了这些生物活性化合物的组成和主要有前途的特性，这些特性可以对动物健康和性能产生有益影响，以及这些植物性饲料添加剂如何帮助减轻真菌毒素的有害影响。
