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未来展望:利用人工智能在新型肽类药物研发中的力量。

Future Perspective: Harnessing the Power of Artificial Intelligence in the Generation of New Peptide Drugs.

机构信息

Institute of Biochemistry, Departments of Biology & Chemistry, Carleton University, Ottawa, ON K1S 5B6, Canada.

NuvoBio Corporation, Ottawa, ON K1S 5B6, Canada.

出版信息

Biomolecules. 2024 Oct 15;14(10):1303. doi: 10.3390/biom14101303.

Abstract

The expansive field of drug discovery is continually seeking innovative approaches to identify and develop novel peptide-based therapeutics. With the advent of artificial intelligence (AI), there has been a transformative shift in the generation of new peptide drugs. AI offers a range of computational tools and algorithms that enables researchers to accelerate the therapeutic peptide pipeline. This review explores the current landscape of AI applications in peptide drug discovery, highlighting its potential, challenges, and ethical considerations. Additionally, it presents case studies and future prospectives that demonstrate the impact of AI on the generation of new peptide drugs.

摘要

药物发现领域正在不断寻求创新方法,以鉴定和开发新型基于肽的疗法。随着人工智能 (AI) 的出现,新型肽类药物的研发发生了变革性转变。AI 提供了一系列计算工具和算法,使研究人员能够加速治疗性肽类药物的研发进程。本综述探讨了 AI 在肽类药物发现中的应用现状,强调了其潜力、挑战和伦理考虑。此外,还介绍了案例研究和未来展望,展示了 AI 在新型肽类药物研发中的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ee0/11505729/467db5919524/biomolecules-14-01303-g001.jpg

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