急性B型病毒性肝炎的复发——丁型肝炎病毒的作用
Relapse of acute B viral hepatitis--role of delta agent.
作者信息
Govindarajan S, Valinluck B, Peters L
出版信息
Gut. 1986 Jan;27(1):19-22. doi: 10.1136/gut.27.1.19.
Abstract
Serologic markers for delta agent were evaluated in 39 patients with acute hepatitis B and clinical relapse within 30 days from the initial episode. Eighteen of the 39 patients (46%) had evidence of acute delta infection. Delta antigenaemia preceded the appearance of antibodies in seven of these 18 patients; delta antigenaemia occurred during the initial episode of illness and the appearance of the antibody coincided with the relapse. Eight of these patients developed severe relapse with fulminant course which resulted in two deaths. This study reveals that delta infection is one of the important causes of severe relapse in cases of acute B viral hepatitis.
摘要
对39例急性乙型肝炎且在初次发病后30天内出现临床复发的患者进行了丁型肝炎病毒血清学标志物评估。39例患者中有18例（46%）有急性丁型肝炎感染的证据。在这18例患者中的7例中，丁型肝炎抗原血症先于抗体出现；丁型肝炎抗原血症在疾病初期发作时出现，抗体出现与复发同时发生。其中8例患者病情严重复发，病程呈暴发性，导致2例死亡。本研究表明，丁型肝炎感染是急性B型病毒性肝炎病例严重复发的重要原因之一。
相似文献
1
Relapse of acute B viral hepatitis--role of delta agent.急性B型病毒性肝炎的复发——丁型肝炎病毒的作用
Gut. 1986 Jan;27(1):19-22. doi: 10.1136/gut.27.1.19.
2
IgM anti-HD in acute hepatitis D: diagnostic and prognostic significance.急性丁型肝炎中的IgM抗-HD：诊断和预后意义
Prog Clin Biol Res. 1987;234:243-8.
3
The role of delta superinfection in acute exacerbations of chronic type B hepatitis.
Liver. 1986 Feb;6(1):26-9. doi: 10.1111/j.1600-0676.1986.tb00264.x.
4
[Delta agent infection and immunoglobulin G in acute HBsAg-positive hepatitis with chronic course].[急性HBsAg阳性慢性病程肝炎中的δ因子感染与免疫球蛋白G]
Boll Ist Sieroter Milan. 1987;66(6):485-8.
5
Fulminant delta hepatitis in chronic hepatitis B infection.慢性乙型肝炎感染中的暴发性丁型肝炎
JAMA. 1984 Nov 16;252(19):2746-8. doi: 10.1001/jama.252.19.2746.
6
[Role of delta infection in fulminant course of viral hepatitis].
Klin Med (Mosk). 1990 Nov;68(11):46-9.
7
Serological response to the hepatitis delta virus in hepatitis D.
Lancet. 1987 Feb 28;1(8531):478-80. doi: 10.1016/s0140-6736(87)92090-3.
8
9
Fulminant B viral hepatitis: role of delta agent.暴发性乙型病毒性肝炎：丁型肝炎病毒的作用
Gastroenterology. 1984 Jun;86(6):1417-20.
10
Incidence of hepatitis delta virus infection in acute HBsAg-negative hepatitis.急性HBsAg阴性肝炎中丁型肝炎病毒感染的发生率。
J Infect Dis. 1989 May;159(5):977-9. doi: 10.1093/infdis/159.5.977.
引用本文的文献
1
Hepatitis D virus infection, replication and cross-talk with the hepatitis B virus.丁型肝炎病毒感染、复制及其与乙型肝炎病毒的相互作用
World J Gastroenterol. 2014 Oct 28;20(40):14589-97. doi: 10.3748/wjg.v20.i40.14589.
2
Hepatitis delta virus RNA in serum of patients with chronic delta hepatitis.慢性丁型肝炎患者血清中的丁型肝炎病毒RNA
Dig Dis Sci. 1994 Dec;39(12):2650-5. doi: 10.1007/BF02087704.
3
Biphasic hepatitis in HBV/HDV coinfected parenteral drug abusers.乙肝病毒/丁型肝炎病毒合并感染的静脉注射吸毒者中的双相性肝炎
Gut. 1986 Jun;27(6):747-8. doi: 10.1136/gut.27.6.747.
4
Clinical features of hepatitis delta virus infection in a northern Italian area.
Infection. 1988;16(6):345-8. doi: 10.1007/BF01644544.
5
Delta and non-A, non-B hepatitis viruses.δ肝炎病毒及非甲非乙型肝炎病毒
Eur J Clin Microbiol Infect Dis. 1988 Jun;7(3):327-36. doi: 10.1007/BF01962332.
6
Medical complications of intravenous drug use.静脉注射吸毒的医学并发症。
J Gen Intern Med. 1990 May-Jun;5(3):249-57. doi: 10.1007/BF02600544.
7
Acute hepatitis B and hepatitis D co-infection in the Stockholm region in the 1970s and 1980s--a comparison.
Infection. 1990 Nov-Dec;18(6):357-60. doi: 10.1007/BF01646405.
8
Correlation of hepatitis B virus, hepatitis D virus and human immunodeficiency virus type I infection markers in hepatitis B surface antigen positive haemophiliacs and patients without haemophilia with clinical and histopathological outcome of hepatitis.乙型肝炎表面抗原阳性血友病患者及非血友病患者中乙型肝炎病毒、丁型肝炎病毒和I型人类免疫缺陷病毒感染标志物与肝炎临床及组织病理学转归的相关性
Eur J Pediatr. 1992 Feb;151(2):90-4. doi: 10.1007/BF01958949.
本文引用的文献
1
Infection with the delta agent in chronic HBsAg carriers.慢性乙肝表面抗原携带者中的丁型肝炎病毒感染。
Gastroenterology. 1981 Dec;81(6):992-7.
2
Infection with delta agent in Sweden: introduction of a new hepatitis agent.瑞典的丁型肝炎病毒感染：一种新型肝炎病原体的出现
J Infect Dis. 1982 Oct;146(4):472-8. doi: 10.1093/infdis/146.4.472.
3
4
IgM antibody to hepatitis B core antigen as a diagnostic parameter of acute infection with hepatitis B virus.乙型肝炎核心抗原IgM抗体作为乙型肝炎病毒急性感染的诊断参数。
J Infect Dis. 1981 Jun;143(6):803-9. doi: 10.1093/infdis/143.6.803.
5
Delta agent infection in Melbourne.墨尔本的丁型肝炎病毒感染
J Med Virol. 1984;13(4):339-45. doi: 10.1002/jmv.1890130404.
6
Fulminant B viral hepatitis: role of delta agent.暴发性乙型病毒性肝炎：丁型肝炎病毒的作用
Gastroenterology. 1984 Jun;86(6):1417-20.
7
Experimental transmission of the delta agent to chimpanzees.
Prog Clin Biol Res. 1983;143:79-89.
8
Clinical aspects of delta infection.δ感染的临床方面。
Br Med J (Clin Res Ed). 1983 Jan 8;286(6359):87-90. doi: 10.1136/bmj.286.6359.87.
9
Chronic hepatitis in carriers of hepatitis B surface antigen, with intrahepatic expression of the delta antigen. An active and progressive disease unresponsive to immunosuppressive treatment.乙肝表面抗原携带者的慢性肝炎，伴有δ抗原的肝内表达。一种对免疫抑制治疗无反应的活动性进行性疾病。
Ann Intern Med. 1983 Apr;98(4):437-41. doi: 10.7326/0003-4819-98-4-437.
Zotero 插件