Gomes P, du Boulay C, Smith C L, Holdstock G
Gut. 1986 Jan;27(1):92-5. doi: 10.1136/gut.27.1.92.
The Crohn's disease activity index, a similar index devised for patients with ulcerative colitis, and other commonly used laboratory indicators of disease activity have been studied in 50 patients with colonic inflammatory bowel disease undergoing routine colonoscopic assessment and compared with the histological extent and activity of disease. There was only poor correlation between the colonoscopic or histological findings and the indices of disease activity studied, showing that these are not reliable measures of disease activity or extent at the tissue level.
对50例接受常规结肠镜检查评估的结肠炎性肠病患者,研究了克罗恩病活动指数(一种为溃疡性结肠炎患者设计的类似指数)以及其他常用的疾病活动实验室指标,并与疾病的组织学范围和活动度进行了比较。结肠镜检查或组织学检查结果与所研究的疾病活动指数之间仅有微弱的相关性,这表明这些指标并非组织水平上疾病活动或范围的可靠测量方法。