Karhunen P J
J Clin Pathol. 1986 Feb;39(2):183-8. doi: 10.1136/jcp.39.2.183.
In a consecutive medicolegal necropsy series benign hepatic tumours and tumour like conditions occurred in 52% of the 95 men aged 35-69 years. The incidence increased with age, mainly due to small bile duct tumours (n = 26; mean age 56.7 years; p less than 0.01; mean size 1.3 mm). The next most common tumours were cavernous hemangiomas (n = 19; mean age 53.9 years; mean size 5.2 mm) that were not related to age. Focal nodular hyperplasia (n = 3; mean size 8.0 mm) tended to occur in a younger age group (mean age 40.3 years; p less than 0.001). Multiple bile duct tumours were present in 46% and hemangiomas in 50% of the men studied. Liver cell adenoma, nodular regenerative hyperplasia, and peliosis hepatis were incidental findings (one case of each). Nodular regenerative hyperplasia was associated with the consumption of alcohol and a total dose of 21.5 g of testosterone. These results indicate that benign hepatic tumours and tumour like conditions are not rare in men but may remain undetected because of their small size.
在一项连续性法医尸检系列研究中，95名年龄在35至69岁的男性中，52%出现了良性肝肿瘤及肿瘤样病变。发病率随年龄增长而增加，主要归因于小胆管肿瘤（26例；平均年龄56.7岁；p<0.01；平均大小1.3毫米）。其次最常见的肿瘤是海绵状血管瘤（19例；平均年龄53.9岁；平均大小5.2毫米），其与年龄无关。局灶性结节性增生（3例；平均大小8.0毫米）倾向于发生在较年轻的年龄组（平均年龄40.3岁；p<0.001）。在研究的男性中，46%存在多发胆管肿瘤，50%存在血管瘤。肝细胞腺瘤、结节性再生性增生和肝紫癜均为偶然发现（各1例）。结节性再生性增生与饮酒及21.5克总睾酮剂量有关。这些结果表明，良性肝肿瘤及肿瘤样病变在男性中并不罕见，但可能因其体积小而未被发现。
