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[普埃布拉一级医院孕妇中与Vaxzevria疫苗相关的事件]

[Events attributable to Vaxzevria vaccine in pregnant women from a first-level hospital in Puebla].

作者信息

Huerta-Rojas Josafath Alan, Bravo-de la Rosa Gabriela, Texis-Ramírez Jesús, Reyes-Tobón Itari Teresa

机构信息

Instituto Mexicano del Seguro Social, Unidad de Medicina Familiar No. 55, Servicio de Medicina Familiar. Puebla, Puebla, México.

Instituto Mexicano del Seguro Social, Unidad de Medicina Familiar No. 34. Servicio de Medicina Familiar. Puebla, Puebla, México.

出版信息

Rev Med Inst Mex Seguro Soc. 2024 Sep 2;62(5):1-6. doi: 10.5281/zenodo.12667969.

Abstract

BACKGROUND

COVID-19 is a severe acute respiratory syndrome caused by SARS-CoV-2. This disease had a high mortality rate and turned into a pandemic, which is why it was considered a severe public health problem. In this context, pregnant patients were a vulnerable group and, consequently, an effective vaccine was necessary.

OBJECTIVE

To categorize the events attributable to the application of Vaxzevria vaccine in pregnant patients.

MATERIAL AND METHODS

Retrospective, cross-sectional, descriptive and observational study carried out at No. 55 Family Medicine Unit in Puebla, Puebla. 300 patients between 15 and 44 years of age who received the first dose of Vaxzevria vaccine were included. The Format of Notification of Events Presumably Attributable to Vaccination was reviewed.

RESULTS

The most representative general symptoms were headache in 44.3%; fever in 30.7%; asthenia and adynamia in 19.3%; adynamia in 19%, and limitation of movement in 3%. Concerning local symptoms and signs, 23% presented localized pain on the site where the vaccine was administered. Finally, regarding systemic symptoms, 21.7% had arthralgias and 20.7% myalgias.

CONCLUSIONS

The symptoms and signs were of less severity for pregnant patients, and resolved in a few days, which is why it was safe the administration of Vaxzevria vaccine.

摘要

背景

新型冠状病毒肺炎(COVID-19)是由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的严重急性呼吸道综合征。这种疾病死亡率高,并演变成了一场大流行,因此被视为一个严重的公共卫生问题。在这种情况下,孕妇是弱势群体,因此需要一种有效的疫苗。

目的

对接种阿斯利康疫苗的孕妇出现的不良反应进行分类。

材料与方法

在普埃布拉州普埃布拉市第55家庭医学单元开展一项回顾性、横断面、描述性观察研究。纳入300名年龄在15至44岁之间且接种了第一剂阿斯利康疫苗的患者。查阅了疑似疫苗接种不良反应报告表。

结果

最具代表性的一般症状为:头痛,占44.3%;发热,占30.7%;乏力和活动减少,各占19.3%;活动减少,占19%;活动受限,占3%。关于局部症状和体征,23%的患者在疫苗接种部位出现局部疼痛。最后,关于全身症状,21.7%的患者有关节痛,20.7%的患者有肌痛。

结论

孕妇出现的症状和体征较轻,且在数天内缓解,因此接种阿斯利康疫苗是安全的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8da2/12408105/d40084d1af03/04435117-62-5-e5831-c001.jpg

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