Theilade D
Anaesthesia. 1979 Nov-Dec;34(10):1028-31. doi: 10.1111/j.1365-2044.1979.tb06253.x.
A 3-week-old baby, suffering from whooping cough with severe attacks of apnoea and hypoxia, was treated by nasal CPAP with a positive airway pressure of about 5 cm H2O. The respiration improved rapidly and the transcutaneous oxygen tension increased to a normal level. The treatment was carried on for 7 days and discontinued gradually in the course of 3 days. The child was also treated with pertussis immunoglobulin and erythromycin. The CPAP system employed is easily and rapidly applied and allows normal nursing of the child during the treatment and manual lung physiotherapy in upright position. The treatment probably proved lifesaving.
一名3周大的婴儿患有百日咳,伴有严重的呼吸暂停和缺氧发作,接受了鼻持续气道正压通气(CPAP)治疗,气道正压约为5厘米水柱。呼吸迅速改善,经皮氧分压升至正常水平。治疗持续了7天,并在3天内逐渐停止。该患儿还接受了百日咳免疫球蛋白和红霉素治疗。所采用的CPAP系统易于快速应用,在治疗期间允许对患儿进行正常护理,并可在直立位进行手动肺部物理治疗。该治疗可能挽救了患儿的生命。