Ellis R E, Sulston J E, Coulson A R
Nucleic Acids Res. 1986 Mar 11;14(5):2345-64. doi: 10.1093/nar/14.5.2345.
We have sequenced one complete rDNA tandem repeat from the nematode C. elegans. By comparative analysis we derive secondary structures for the 18s, 5.8s, and 26s rRNA molecules, and comment on other important features of the sequence. We also present the sequence of a junction between the rDNA and non-ribosomal DNA. Finally, we use our data to quantify the evolutionary relationships among several organisms currently studied in developmental biology.
我们已对来自秀丽隐杆线虫的一个完整核糖体DNA串联重复序列进行了测序。通过比较分析,我们推导了18s、5.8s和26s核糖体RNA分子的二级结构,并对该序列的其他重要特征进行了评论。我们还展示了核糖体DNA与非核糖体DNA之间连接区域的序列。最后,我们利用我们的数据对目前发育生物学中所研究的几种生物之间的进化关系进行了量化。