Department of Biotechnology, Sangmyung University, 03016, Seoul, Republic of Korea.
Sci Rep. 2024 Nov 30;14(1):29786. doi: 10.1038/s41598-024-81159-7.
Transcription factors (TFs) are essential regulators of gene expression, influencing numerous biological processes such as development, growth, and cellular responses in plants. Among these, GATA TFs are distinguished by their highly conserved DNA-binding domain, characterized by a class IV zinc finger motif (CXCXCXC). This study investigates the amino acid sequence patterns of 5,335 GATA TFs across 165 plant species sourced from the PlantTFDB database ( http://planttfdb.gao-lab.org/ ), encompassing diverse taxonomic groups. Through comparative sequence analysis, I identify conserved domains and structural features that enhance the understanding functional roles, evolutionary conservation, and lineage-specific adaptations of GATA TFs. These findings provide valuable insights into the diversification and functional specialization of GATA TFs, with implications for improving stress tolerance and adaptability in crops. This study contributes to the broader knowledge of transcriptional regulation in plant biology.
转录因子(TFs)是基因表达的重要调控因子,影响植物的许多生物学过程,如发育、生长和细胞反应。在这些转录因子中,GATA 转录因子因其高度保守的 DNA 结合域而与众不同,其特征是具有一个 IV 类锌指模体(CXCXCXC)。本研究通过比较序列分析,从 PlantTFDB 数据库(http://planttfdb.gao-lab.org/)中研究了 165 种植物物种的 5335 个 GATA 转录因子的氨基酸序列模式,涵盖了不同的分类群。本研究调查了来自 PlantTFDB 数据库(http://planttfdb.gao-lab.org/)的 165 个植物物种的 5335 个 GATA 转录因子的氨基酸序列模式,涵盖了不同的分类群。通过比较序列分析,确定了保守结构域和结构特征,增强了对 GATA 转录因子的功能作用、进化保守性和谱系特异性适应性的理解。这些发现为 GATA 转录因子的多样化和功能特化提供了有价值的见解,对提高作物的抗逆性和适应性具有重要意义。本研究为植物生物学中的转录调控提供了更广泛的知识。