• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

通过物理吸附增强脂肪酶固定化：稳定性、可重复使用性及可持续生物技术过程工业应用方面的进展

Enhancing Lipase Immobilization via Physical Adsorption: Advancements in Stability, Reusability, and Industrial Applications for Sustainable Biotechnological Processes.

作者信息

Silva Almeida Cinthia, Simão Neto Francisco, da Silva Sousa Patrick, da Silva Aires Francisco Izaias, de Matos Filho José Roberto, Gama Cavalcante Antônio Luthierre, Sousa Junior Paulo Gonçalves de, Melo Rafael Leandro Fernandes, S Dos Santos José C

机构信息

Departamento de Engenharia Química, Universidade Federal do Ceará, Campus do Pici, Bloco 709, Fortaleza, CEP 60455760 Ceará, Brazil.

Instituto de Engenharias e Desenvolvimento Sustentável, Universidade da Integração Internacional da Lusofonia Afro-Brasileira, Campus das Auroras, Redenção, CEP 62790970 Ceará, Brazil.

出版信息

ACS Omega. 2024 Nov 14;9(47):46698-46732. doi: 10.1021/acsomega.4c07088. eCollection 2024 Nov 26.

DOI:10.1021/acsomega.4c07088
PMID:39619502
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11603209/
Abstract

Immobilization of lipases by physical adsorption improves their stability, recovery, and reusability in biotechnological processes. The present review provides an advanced bibliometric analysis and a comprehensive overview of research progress in this field. By searching Web of Science, 39,575 publications were analyzed, and 325 relevant articles were selected. Key journals, countries, institutions, and authors were identified. The most cited articles focus on biofuel production and industrial applications. The analysis revealed four research themes with a focus on the production of biofuel. The physical adsorption method is effective when the appropriate support is used. Despite a decrease in patent applications, industrial interest remains high. Future studies should focus on optimizing support materials and exploring new applications of this technique. The present review provides a detailed understanding of the immobilization of lipases by physical adsorption.

摘要

通过物理吸附固定化脂肪酶可提高其在生物技术过程中的稳定性、回收率和可重复使用性。本综述提供了该领域先进的文献计量分析和研究进展的全面概述。通过检索科学网，分析了39575篇出版物，并筛选出325篇相关文章。确定了关键期刊、国家、机构和作者。被引用次数最多的文章集中在生物燃料生产和工业应用方面。分析揭示了四个以生物燃料生产为重点的研究主题。当使用合适的载体时，物理吸附法是有效的。尽管专利申请有所减少，但行业兴趣仍然很高。未来的研究应集中在优化载体材料和探索该技术的新应用上。本综述提供了对通过物理吸附固定化脂肪酶的详细理解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/b4646b87a200/ao4c07088_0014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/867b9c96d4c5/ao4c07088_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/cac6a8e1ecee/ao4c07088_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/ccf888900b0b/ao4c07088_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/444228fd3a9f/ao4c07088_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/844e8b7f953e/ao4c07088_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/36062ce0638b/ao4c07088_0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/cdf55ef92881/ao4c07088_0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/adfba0aebf49/ao4c07088_0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/a8746a45839e/ao4c07088_0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/b89e20876192/ao4c07088_0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/6355a9124324/ao4c07088_0011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/80b9815b0a3f/ao4c07088_0012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/1ff691f910e8/ao4c07088_0013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/b4646b87a200/ao4c07088_0014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/867b9c96d4c5/ao4c07088_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/cac6a8e1ecee/ao4c07088_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/ccf888900b0b/ao4c07088_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/444228fd3a9f/ao4c07088_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/844e8b7f953e/ao4c07088_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/36062ce0638b/ao4c07088_0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/cdf55ef92881/ao4c07088_0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/adfba0aebf49/ao4c07088_0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/a8746a45839e/ao4c07088_0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/b89e20876192/ao4c07088_0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/6355a9124324/ao4c07088_0011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/80b9815b0a3f/ao4c07088_0012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/1ff691f910e8/ao4c07088_0013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a36/11603209/b4646b87a200/ao4c07088_0014.jpg

相似文献

1
Enhancing Lipase Immobilization via Physical Adsorption: Advancements in Stability, Reusability, and Industrial Applications for Sustainable Biotechnological Processes.通过物理吸附增强脂肪酶固定化：稳定性、可重复使用性及可持续生物技术过程工业应用方面的进展
ACS Omega. 2024 Nov 14;9(47):46698-46732. doi: 10.1021/acsomega.4c07088. eCollection 2024 Nov 26.
2
Recent applications and future prospects of magnetic biocatalysts.磁性生物催化剂的近期应用及未来展望。
Int J Biol Macromol. 2023 Dec 31;253(Pt 3):126709. doi: 10.1016/j.ijbiomac.2023.126709. Epub 2023 Sep 9.
3
Temperature-resistant and solvent-tolerant lipases as industrial biocatalysts: Biotechnological approaches and applications.耐高温耐溶剂脂肪酶作为工业生物催化剂：生物技术方法及应用。
Int J Biol Macromol. 2021 Sep 30;187:127-142. doi: 10.1016/j.ijbiomac.2021.07.101. Epub 2021 Jul 21.
4
Trends in the Use of Lipases: A Systematic Review and Bibliometric Analysis.脂肪酶使用趋势：系统评价与文献计量分析
Foods. 2023 Aug 15;12(16):3058. doi: 10.3390/foods12163058.
5
Lipases: sources, immobilization methods, and industrial applications.脂肪酶：来源、固定化方法及工业应用。
Appl Microbiol Biotechnol. 2019 Sep;103(18):7399-7423. doi: 10.1007/s00253-019-10027-6. Epub 2019 Aug 2.
6
Lipase immobilization on ceramic supports: An overview on techniques and materials.脂肪酶在陶瓷载体上的固定化：技术和材料概述。
Biotechnol Adv. 2020 Sep-Oct;42:107581. doi: 10.1016/j.biotechadv.2020.107581. Epub 2020 Jun 23.
7
A Comprehensive Guide to Enzyme Immobilization: All You Need to Know.酶固定化综合指南：你需要了解的一切。
Molecules. 2025 Feb 18;30(4):939. doi: 10.3390/molecules30040939.
8
The Top 100 Cited Articles Focusing on Acute Lung Injury and ARDS: Bibliometric and Visualization Analyses.100 篇聚焦急性肺损伤和急性呼吸窘迫综合征的高被引文章：计量学和可视化分析。
Respir Care. 2024 Jul 24;69(8):959-967. doi: 10.4187/respcare.11616.
9
Enhancing rhamnolipid production via immobilized Pseudomonas stutzeri lipase: A comparative study.通过固定化施氏假单胞菌脂肪酶提高鼠李糖脂产量：一项比较研究。
Bioorg Chem. 2024 Dec;153:107855. doi: 10.1016/j.bioorg.2024.107855. Epub 2024 Oct 9.
10
Innovative approaches for enzyme immobilization in milk processing: advancements and industrial applications.牛奶加工中酶固定化的创新方法：进展与工业应用
Crit Rev Food Sci Nutr. 2025 Jan 22:1-20. doi: 10.1080/10408398.2025.2450528.

引用本文的文献

1
Nanoengineered Enzyme Immobilization: Toward Biomedical, Orthopedic, and Biofuel Applications.纳米工程酶固定化：迈向生物医学、矫形外科和生物燃料应用
ACS Omega. 2025 Aug 5;10(32):35434-35450. doi: 10.1021/acsomega.5c05589. eCollection 2025 Aug 19.
2
Enzymatic Hydroesterification of Waste Oils: Combilipase-Assisted Ethyl Ester Synthesis via a Dual-Step Biocatalytic Process.废油的酶促加氢酯化反应：通过双步生物催化过程的组合脂肪酶辅助乙酯合成
ACS Omega. 2025 May 16;10(20):20623-20637. doi: 10.1021/acsomega.5c01442. eCollection 2025 May 27.
3
Sustainable Alternative Media for the Production of Lipolytic Cells and Fatty Acid Concentrates: Integration of the Enzyme and Food Industries.

本文引用的文献

1
Advancements in enzyme immobilization on magnetic nanomaterials: toward sustainable industrial applications.磁性纳米材料上酶固定化的进展：迈向可持续工业应用
RSC Adv. 2024 Jun 5;14(25):17946-17988. doi: 10.1039/d4ra02939a. eCollection 2024 May 28.
2
Application of Hierarchically Porous Chitosan Monolith for Enzyme Immobilization.层状多孔壳聚糖整体的酶固定化应用。
Biomacromolecules. 2024 Jun 10;25(6):3486-3498. doi: 10.1021/acs.biomac.4c00109. Epub 2024 May 8.
3
Natural and Synthetic Polymers for Biomedical and Environmental Applications.
用于生产脂肪分解细胞和脂肪酸浓缩物的可持续替代介质：酶产业与食品产业的整合
Foods. 2025 Mar 14;14(6):990. doi: 10.3390/foods14060990.
4
Advances and Applications of Micro- and Mesofluidic Systems.微纳流体系统的进展与应用
ACS Omega. 2025 Mar 25;10(13):12817-12836. doi: 10.1021/acsomega.4c10999. eCollection 2025 Apr 8.
5
Heterologous expression and enzymatic properties of lipase from Mucor circinelloides.卷枝毛霉脂肪酶的异源表达及酶学性质
Sci Rep. 2025 Mar 29;15(1):10871. doi: 10.1038/s41598-025-93938-x.
6
Global Advancements in Bioactive Material Manufacturing for Drug Delivery: A Comprehensive Study.用于药物递送的生物活性材料制造的全球进展：一项综合研究。
ACS Omega. 2025 Jan 3;10(1):1207-1225. doi: 10.1021/acsomega.4c08669. eCollection 2025 Jan 14.
7
Advancements and Prospects in Nanorobotic Applications for Ophthalmic Therapy.眼科治疗中纳米机器人应用的进展与前景
ACS Biomater Sci Eng. 2025 Feb 10;11(2):958-980. doi: 10.1021/acsbiomaterials.4c02368. Epub 2025 Jan 17.
用于生物医学和环境应用的天然与合成聚合物。
Polymers (Basel). 2024 Apr 20;16(8):1159. doi: 10.3390/polym16081159.
4
Automated in vivo enzyme engineering accelerates biocatalyst optimization.自动化体内酶工程加速生物催化剂优化。
Nat Commun. 2024 Apr 24;15(1):3447. doi: 10.1038/s41467-024-46574-4.
5
Green Enzymatic Synthesis of Geranyl Butyrate: Process Optimization and Mechanistic Insights.香叶醇丁酸酯的绿色酶法合成：工艺优化与机理洞察
ACS Omega. 2024 Apr 1;9(15):16992-17001. doi: 10.1021/acsomega.3c08483. eCollection 2024 Apr 16.
6
A comprehensive review on enzyme-based biosensors: Advanced analysis and emerging applications in nanomaterial-enzyme linkage.基于酶的生物传感器的全面综述：纳米材料-酶结合物中的高级分析和新兴应用。
Int J Biol Macromol. 2024 Apr;264(Pt 2):130817. doi: 10.1016/j.ijbiomac.2024.130817. Epub 2024 Mar 11.
7
Enhancing biocatalyst performance through immobilization of lipase (Eversa® Transform 2.0) on hybrid amine-epoxy core-shell magnetic nanoparticles.通过将脂肪酶（Eversa® Transform 2.0）固定在混合胺-环氧核壳磁性纳米颗粒上提高生物催化剂性能。
Int J Biol Macromol. 2024 Apr;264(Pt 2):130730. doi: 10.1016/j.ijbiomac.2024.130730. Epub 2024 Mar 10.
8
Recent advances in the design and immobilization of heparin for biomedical application: A review.近年来肝素在生物医学应用中的设计和固定化的研究进展：综述。
Int J Biol Macromol. 2024 Apr;264(Pt 2):130743. doi: 10.1016/j.ijbiomac.2024.130743. Epub 2024 Mar 9.
9
Review on sterilization techniques, and the application potential of phage lyase and lyase immobilization in fighting drug-resistant bacteria.关于灭菌技术的综述，以及噬菌体裂解酶及其固定化技术在抗药性细菌方面的应用潜力。
J Mater Chem B. 2024 Apr 3;12(14):3317-3335. doi: 10.1039/d3tb02366d.
10
Mechanisms of adsorption and functionalization of biochar for pesticides: A review.生物炭对农药的吸附和功能化机制：综述。
Ecotoxicol Environ Saf. 2024 Mar 1;272:116019. doi: 10.1016/j.ecoenv.2024.116019. Epub 2024 Jan 30.