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磁性生物催化剂的近期应用及未来展望。

Recent applications and future prospects of magnetic biocatalysts.

机构信息

Departamento de Engenharia Metalúrgica e de Materiais, Universidade Federal do Ceará, Campus do Pici, Bloco 729, Fortaleza CEP 60440-554, CE, Brazil; Grupo de Química de Materiais Avançados (GQMat), Departamento de Química Analítica e Físico-Química, Universidade Federal do Ceará, Campus do Pici, Fortaleza CEP 60451-970, CE, Brazil.

Instituto de Engenharias e Desenvolvimento Sustentável, Universidade da Integração Internacional da Lusofonia Afro-Brasileira, Campus das Auroras, Redenção CEP 62790-970, CE, Brazil.

出版信息

Int J Biol Macromol. 2023 Dec 31;253(Pt 3):126709. doi: 10.1016/j.ijbiomac.2023.126709. Epub 2023 Sep 9.

Abstract

Magnetic biocatalysts combine magnetic properties with the catalytic activity of enzymes, achieving easy recovery and reuse in biotechnological processes. Lipases immobilized by magnetic nanoparticles dominate. This review covers an advanced bibliometric analysis and an overview of the area, elucidating research advances. Using WoS, 34,949 publications were analyzed and refined to 450. The prominent journals, countries, institutions, and authors that published the most were identified. The most cited articles showed research hotspots. The analysis of the themes and keywords identified five clusters and showed that the main field of research is associated with obtaining biofuels derived from different types of sustainable vegetable oils. The overview of magnetic biocatalysts showed that these materials are also employed in biosensors, photothermal therapy, environmental remediation, and medical applications. The industry shows a significant interest, with the number of patents increasing. Future studies should focus on immobilizing new lipases in unique materials with magnetic profiles, aiming to improve the efficiency for various biotechnological applications.

摘要

磁性生物催化剂将磁性与酶的催化活性相结合,在生物技术过程中实现了易于回收和再利用。磁性纳米粒子固定化的脂肪酶占据主导地位。本综述涵盖了高级文献计量分析和该领域的概述,阐明了研究进展。使用 WoS,分析了 34949 篇出版物,并精减至 450 篇。确定了发表数量最多的突出期刊、国家、机构和作者。最具引用价值的文章显示了研究热点。对主题和关键词的分析确定了五个聚类,表明主要的研究领域与获得不同类型可持续植物油衍生的生物燃料有关。磁性生物催化剂的概述表明,这些材料还应用于生物传感器、光热疗法、环境修复和医学应用。该行业表现出极大的兴趣,专利数量不断增加。未来的研究应集中于在具有独特磁性特征的材料中固定化新的脂肪酶,以提高各种生物技术应用的效率。

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