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非药物干预措施的社会困境:动态依从性和行为转变的决定因素

Social dilemma of nonpharmaceutical interventions: Determinants of dynamic compliance and behavioral shifts.

作者信息

Glaubitz Alina, Fu Feng

机构信息

Department of Mathematics, Dartmouth College, Hanover, NH 03755.

Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756.

出版信息

Proc Natl Acad Sci U S A. 2024 Dec 10;121(50):e2407308121. doi: 10.1073/pnas.2407308121. Epub 2024 Dec 4.

Abstract

In fighting infectious diseases posing a global health threat, ranging from influenza to Zika, nonpharmaceutical interventions (NPI), such as social distancing and face covering, remain mitigation measures public health can resort to. However, the success of NPI lies in sufficiently high levels of collective compliance, otherwise giving rise to recurrent infections that are not only driven by pathogen evolution but also changing vigilance in the population. Here, we show that compliance with each NPI measure can be highly dynamic and context-dependent during an ongoing epidemic, where individuals may prefer one to another or even do nothing, leading to intricate temporal switching behavior of NPI adoptions. By characterizing dynamic regimes through the perceived costs of NPI measures and their effectiveness in particular regarding face covering and social distancing, our work offers insights into overcoming barriers in NPI adoptions.

摘要

在对抗从流感到寨卡病毒等构成全球健康威胁的传染病时,非药物干预措施(NPI),如社交距离和佩戴口罩,仍然是公共卫生可以采用的缓解措施。然而,非药物干预措施的成功取决于足够高的集体依从水平,否则会导致反复感染,这不仅是由病原体进化驱动的,还与人群中不断变化的警惕性有关。在这里,我们表明,在持续的疫情期间,对每项非药物干预措施的依从性可能高度动态且依赖于具体情况,在此期间,个体可能更喜欢一种措施而不是另一种措施,甚至什么都不做,从而导致非药物干预措施采用的复杂时间切换行为。通过根据非药物干预措施的感知成本及其在特别是佩戴口罩和保持社交距离方面的有效性来表征动态模式,我们的工作为克服非药物干预措施采用中的障碍提供了见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb14/11648666/be97714d280f/pnas.2407308121fig01.jpg

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