Bozer Burak Doğan, Dede Alper, Güven Kıymet
Department of Advanced Technologies, Institute of Graduate Programs, Eskişehir Technical University, 26470 Eskişehir, Turkey.
Department of Biology, Institute of Graduate Programs, Eskişehir Technical University, 26470 Eskişehir, Turkey.
Indian J Microbiol. 2024 Dec;64(4):1903-1911. doi: 10.1007/s12088-024-01276-9. Epub 2024 Apr 22.
For the past few years, the synthesis of zinc oxide (ZnO) and other metal oxide nanoparticles has been carried out using plant tissues, extracts, and other plant parts. The green synthesis of zinc oxide nanoparticles has many advantages over other processes, and the primary areas of application are drug delivery, food additives, and surface coatings. The use of nanoparticles as an alternative antimicrobial agent in the health and biomedical sectors has increased significantly in recent years. This study explores the antimicrobial activities of zinc oxide nanoparticles synthesized via a green method using L., which is commonly known as miswak plant extracts, and their potential application in a mouthwash formulation. First, we produced the nanoparticles with green synthesis, and the second was merging the nanoparticles with the mouthwash formulation. In post-production of nanoparticles, antimicrobial activities were screened using the agar well diffusion method on , , , , , , , . In addition, Fourier transform infrared (FT-IR), UV-VIS spectroscopy, and scanning electron microscope were used for the characterization of the synthesized nanoparticles. In summary, polymorphic and spherical morphologies of zinc oxide nanoparticles were generated. While mouthwash made with NP-3 coded nanoparticles and mouthwash made with NP-9 coded nanoparticles had the highest antibacterial activity on , NP-3 coded ZnO nanoparticles and NP-9 coded ZnO nanoparticles had the highest antimicrobial activity on . Diverse effects of the nanomaterials were observed; it is intended to lead future research.
The online version contains supplementary material available at 10.1007/s12088-024-01276-9.
在过去几年中，已经使用植物组织、提取物和其他植物部分来合成氧化锌（ZnO）和其他金属氧化物纳米颗粒。氧化锌纳米颗粒的绿色合成相对于其他方法具有许多优点，其主要应用领域包括药物递送、食品添加剂和表面涂层。近年来，纳米颗粒作为健康和生物医学领域的替代抗菌剂的使用显著增加。本研究探索了通过绿色方法使用通常被称为牙刷树提取物的植物提取物合成的氧化锌纳米颗粒的抗菌活性及其在漱口水配方中的潜在应用。首先，我们通过绿色合成制备了纳米颗粒，其次是将纳米颗粒与漱口水配方合并。在纳米颗粒生产后，使用琼脂扩散法在……上筛选抗菌活性。此外，使用傅里叶变换红外光谱（FT-IR）、紫外可见光谱和扫描电子显微镜对合成的纳米颗粒进行表征。总之，生成了氧化锌纳米颗粒的多晶型和球形形态。虽然用NP-3编码的纳米颗粒制成的漱口水和用NP-9编码的纳米颗粒制成的漱口水对……具有最高的抗菌活性，但NP-3编码的氧化锌纳米颗粒和NP-9编码的氧化锌纳米颗粒对……具有最高的抗菌活性。观察到了纳米材料的不同效果；这旨在引领未来的研究。
在线版本包含可在10.1007/s12088-024-01276-9获取的补充材料。
