Chen Luo, Shuang Han, Qingjian Wu, Jingzhen Zhu, Ji Zheng, Yu Chen
Department of Urology, Urologic Surgery Center, Xinqiao Hospital, The Second Affiliated Hospital of Army Medical University, Third Military Medical University ), Chongqing, 400037, China.
State Key Laboratory of Trauma and Chemical Poisoning, Third Military Medical University (Army Medical University), Chongqing, 400042, China.
BMC Urol. 2024 Dec 20;24(1):271. doi: 10.1186/s12894-024-01663-w.
This study aimed to gather and assess the most reliable evidence on bone health management in patients undergoing endocrine therapy for prostate cancer, with the goal of informing clinical practice.
Utilizing the '6S' evidence model, a comprehensive literature search was conducted across various sources such as computerized decision support systems, national and international guideline networks, society websites, and databases encompassing clinical decision-making, guidelines, systematic reviews, evidence summaries, and expert consensus. The search spanned from April 2014 to April 2024, with two researchers independently evaluating the quality of the identified literature.
A total of 12 articles were included, comprising 6 clinical guidelines, 5 expert consensus papers, and 1 systematic evaluation. The findings were categorized into risk assessment, prevention, and interventions for osteoporosis and fractures, yielding 26 pieces of best evidence.
This study synthesized key evidence on bone health management for prostate cancer patients undergoing endocrine therapy, emphasizing the importance of healthcare professionals utilizing this evidence to develop and implement effective bone health management strategies to mitigate the risk of osteoporosis and fractures.
本研究旨在收集和评估接受前列腺癌内分泌治疗患者骨健康管理方面最可靠的证据，以为临床实践提供参考。
利用“6S”证据模型，在计算机化决策支持系统、国家和国际指南网络、学会网站以及涵盖临床决策、指南、系统评价、证据总结和专家共识的数据库等各种来源中进行全面的文献检索。检索时间跨度为2014年4月至2024年4月，由两名研究人员独立评估所确定文献的质量。
共纳入12篇文章，包括6篇临床指南、5篇专家共识论文和1篇系统评价。研究结果分为骨质疏松症和骨折的风险评估、预防及干预，共产生26条最佳证据。
本研究综合了接受内分泌治疗的前列腺癌患者骨健康管理的关键证据，强调医疗保健专业人员利用这些证据制定和实施有效的骨健康管理策略以降低骨质疏松症和骨折风险的重要性。
