Wang Zhikang, Pu Rui, Zhang Jing, Wang Ying, Yang Guoli
Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, 310000, Hangzhou, China.
Zhejiang Provincial Clinical Research Center for Oral Diseases Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, 310017, Hangzhou, China.
Clin Oral Investig. 2024 Dec 31;29(1):37. doi: 10.1007/s00784-024-06117-z.
To explore the relationship between Life's Essential 8 (LE-8) and periodontitis, specifically focusing on identifying the specific factors within LE-8 significantly linked to periodontitis.
This cross-sectional study utilized data from the National Health and Nutrition Examination Survey (2009-2014), involving 8160 participants with available LE-8 metrics and periodontal examination results. The LE-8 metrics, encompassing diet, physical activity, nicotine exposure, sleep health, body mass index, blood liquids, blood glucose, and blood pressure were collected for analysis. Periodontitis diagnosis followed CDC-AAP guidelines.
4049 subjects with periodontitis (mean age, 54.80 years; 57.93% male) and 4111 subjects without periodontitis (mean age, 48.66 years; 42.61% male) were included in this study. Periodontitis subjects had lower total LE-8 scores (64.62 [63.94, 65.30]) than periodontitis-free subjects (71.34 [70.65, 72.03]). The risk of periodontitis risk significantly decreased with increasing LE-8 score. Specific factors within LE-8, including avoidance of nicotine (Adjusted OR = 0.90 [0.88, 0.92]), healthy sleep (Adjusted OR = 0.95 [0.92, 0.99]), and healthy levels of blood glucose (Adjusted OR = 0.94 [0.90, 0.98]) were negatively associated with periodontitis presences.
Higher scores in life's essential 8 metrics, particularly in nicotine exposure, sleep health, and blood glucose, may benefit periodontal health.
Adopting a healthy lifestyle reduces the risk of periodontitis. Avoiding smoking, sufficient sleep, and stable blood glucose are linked to lower periodontitis risk. Healthcare professionals should advise individuals with lower life's essential 8 scores to prioritize oral care.
探讨生命必需8要素（LE-8）与牙周炎之间的关系，特别关注确定LE-8中与牙周炎显著相关的具体因素。
这项横断面研究利用了国家健康与营养检查调查（2009 - 2014年）的数据，涉及8160名有可用LE-8指标和牙周检查结果的参与者。收集了包括饮食、身体活动、尼古丁暴露、睡眠健康、体重指数、血液、血糖和血压在内的LE-8指标进行分析。牙周炎诊断遵循美国疾病控制与预防中心-美国牙周病学会指南。
本研究纳入了4049名患有牙周炎的受试者（平均年龄54.80岁；男性占57.93%）和4111名无牙周炎的受试者（平均年龄48.66岁；男性占42.61%）。患有牙周炎的受试者的LE-8总得分（64.62 [63.94, 65.30]）低于无牙周炎的受试者（71.34 [70.65, 72.03]）。牙周炎风险随着LE-8得分的增加而显著降低。LE-8中的具体因素，包括避免尼古丁暴露（调整后比值比=0.90 [0.88, 0.92]）、健康睡眠（调整后比值比=0.95 [0.92, 0.99]）和血糖水平正常（调整后比值比=0.94 [0.90, 0.98]）与牙周炎的存在呈负相关。
生命必需8要素指标得分较高，尤其是在尼古丁暴露、睡眠健康和血糖方面，可能有益于牙周健康。
采用健康的生活方式可降低患牙周炎的风险。避免吸烟、充足睡眠和稳定的血糖与较低的牙周炎风险相关。医疗保健专业人员应建议生命必需8要素得分较低的个体优先进行口腔护理。
