Islam Mohammad Jahirul, Ahmed Sohel, Kamrul Islam Khandaker Md, Tina Progya Laboni, Nath Ayon Deb, Biswas Nipa, Islam Md Shafiqul, Dey Shikder Bikash Juty, Al Mamun Muhammed Abdullah, Yasmin Nasima, Chakraborty Shishir Ranjan
MAG Osmani Medical College Hospital, Sylhet, Bangladesh.
Ahmed Physiotherapy & Research Center, Kalabagan, Dhaka, Bangladesh.
PLoS One. 2025 Jan 3;20(1):e0311325. doi: 10.1371/journal.pone.0311325. eCollection 2025.
Poststroke depression (PSD) is a highly prevalent and serious mental health condition affecting a significant proportion of stroke survivors worldwide. While its exact causes remain under investigation, managing PSD presents a significant challenge.
This study aimed to evaluate the prevalence and predictors of depression among Bangladeshi stroke victims.
A cross-sectional study was carried out with 725 stroke victims who were receiving medical care at three designated tertiary care hospitals in Sylhet from January to December 2023. Depression and disability were measured using the Patient Health Questionnaire-9 and the Modified Rankin Scale. Logistic regression analysis was employed to examine the predictors linked to depression.
According to the study, 80.8% of individuals had moderate to severe disability, and 58.1% of them experienced a moderate to severe level of depression. Individuals who had hemorrhagic stroke (AOR 1.31, 95% CI: 0.77-2.25), repeated episodes (AOR 3.41, 95% CI: 1.89-6.14), tobacco use (AOR 1.76, 95% CI: 1.16-2.67), or coexisting health conditions (AOR 1.68, 95% CI: 1.00-2.82) exhibited elevated levels of depression. Participants whose medical expenses covered by relatives or others were six times more likely to experience depressive symptoms (AOR 6.32, 95% CI: 1.61-24.76). Individuals who did not receive rehabilitation services had two times greater odds of being depressed (OR 1.85, 95% CI: 1.23-2.77, p = 0.003). Consequently, individuals with low functional status had eleven times greater levels of depression (AOR 11.03, 95% CI: 7.14-17.04).
More than half of the participants in this present study reported moderate to extreme levels of depression which is a serious health issue among Bangladeshi stroke survivors. Understanding the predictors of depression linked to stroke could enhance the effectiveness of therapeutic interventions for this condition. In addition, multidisciplinary teams should work collaboratively to address this serious issue.
中风后抑郁（PSD）是一种高度普遍且严重的心理健康状况，影响着全球相当比例的中风幸存者。尽管其确切病因仍在研究中，但管理PSD是一项重大挑战。
本研究旨在评估孟加拉国中风患者中抑郁的患病率及预测因素。
2023年1月至12月，在锡尔赫特的三家指定三级护理医院对725名接受医疗护理的中风患者进行了一项横断面研究。使用患者健康问卷-9和改良Rankin量表测量抑郁和残疾情况。采用逻辑回归分析来检验与抑郁相关的预测因素。
根据该研究，80.8%的个体有中度至重度残疾，其中58.1%经历了中度至重度抑郁。患有出血性中风的个体（调整后比值比[AOR] 1.31，95%置信区间[CI]：0.77 - 2.25）、有复发发作的个体（AOR 3.41，95% CI：1.89 - 6.14）、吸烟的个体（AOR 1.76，95% CI：1.16 - 2.67）或有并存健康状况的个体（AOR 1.68，95% CI：1.00 - 2.82）抑郁水平较高。医疗费用由亲属或其他人支付的参与者出现抑郁症状的可能性高出六倍（AOR 6.32，95% CI：1.61 - 24.76）。未接受康复服务的个体抑郁的几率高出两倍（比值比[OR] 1.85，95% CI：1.23 - 2.77，p = 0.003）。因此，功能状态低的个体抑郁水平高出十一倍（AOR 11.03，95% CI：7.14 - 17.04）。
本研究中超过一半的参与者报告有中度至重度抑郁，这在孟加拉国中风幸存者中是一个严重的健康问题。了解与中风相关的抑郁预测因素可以提高针对这种情况的治疗干预效果。此外，多学科团队应协同合作来解决这一严重问题。
