接种各种人类肠道细菌的悉生小鼠肠道中艰难梭菌细胞毒素产生的调节
Modulation of cytotoxin production by Clostridium difficile in the intestinal tracts of gnotobiotic mice inoculated with various human intestinal bacteria.
作者信息
Corthier G, Dubos F, Raibaud P
出版信息
Appl Environ Microbiol. 1985 Jan;49(1):250-2. doi: 10.1128/aem.49.1.250-252.1985.
Abstract
Gnotobiotic mice died 2 days after inoculation of a cytotoxigenic Clostridium difficile strain. Protection occurred when mice were previously inoculated with a strain of Escherichia coli or Bifidobacterium bifidum. Intestinal cytotoxin production was highly reduced in the surviving mice, whereas the C. difficile population level did not decrease to a great extent.
摘要
无菌小鼠在接种产细胞毒素的艰难梭菌菌株后2天死亡。若小鼠预先接种大肠杆菌或双歧双歧杆菌菌株，则可获得保护。存活小鼠的肠道细胞毒素产生大幅减少，而艰难梭菌的菌量水平并未大幅下降。
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本文引用的文献
1
Epidemiology of experimental enterocecitis due to Clostridium difficile.艰难梭菌所致实验性小肠结肠炎的流行病学
J Infect Dis. 1980 Sep;142(3):408-13. doi: 10.1093/infdis/142.3.408.
2
Effects of the two toxins of Clostridium difficile in antibiotic-associated cecitis in hamsters.艰难梭菌的两种毒素在仓鼠抗生素相关性盲肠炎中的作用。
Infect Immun. 1982 May;36(2):822-9. doi: 10.1128/iai.36.2.822-829.1982.
3
Biological activities of toxins A and B of Clostridium difficile.艰难梭菌毒素A和毒素B的生物学活性
Infect Immun. 1982 Mar;35(3):1147-50. doi: 10.1128/iai.35.3.1147-1150.1982.
4
Purification and characterization of toxins A and B of Clostridium difficile.艰难梭菌毒素A和毒素B的纯化与特性分析
Infect Immun. 1982 Mar;35(3):1032-40. doi: 10.1128/iai.35.3.1032-1040.1982.
5
Antagonism of toxigenic Clostridium difficile by nontoxigenic C. difficile.无毒力艰难梭菌对产毒艰难梭菌的拮抗作用
J Infect Dis. 1983 Apr;147(4):733-6. doi: 10.1093/infdis/147.4.733.
6
Pseudomembranous colitis in Clostridium difficile-monoassociated rats.艰难梭菌单关联大鼠的假膜性结肠炎
Infect Immun. 1983 Mar;39(3):1368-76. doi: 10.1128/iai.39.3.1368-1376.1983.
7
Toxin A of Clostridium difficile: production, purification and effect in mouse intestine.艰难梭菌毒素A：在小鼠肠道中的产生、纯化及作用
Acta Pathol Microbiol Immunol Scand B. 1983 Dec;91(6):395-400. doi: 10.1111/j.1699-0463.1983.tb00066.x.
8
Isolation of anaerobic bacteria from human gingiva and mouse cecum by means of a simplified glove box procedure.通过简化的手套箱程序从人牙龈和小鼠盲肠中分离厌氧细菌。
Appl Microbiol. 1969 Apr;17(4):568-76. doi: 10.1128/am.17.4.568-576.1969.
9
Identification of Clostridium difficile as a cause of pseudomembranous colitis.艰难梭菌被鉴定为伪膜性结肠炎的病因。
Br Med J. 1978 Mar 18;1(6114):695. doi: 10.1136/bmj.1.6114.695.
10
Antibiotic-associated pseudomembranous colitis due to toxin-producing clostridia.由产毒素梭状芽孢杆菌引起的抗生素相关性假膜性结肠炎。
N Engl J Med. 1978 Mar 9;298(10):531-4. doi: 10.1056/NEJM197803092981003.
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