Mor Rahul R, Shanti Hiba
Minimal Access Surgery, King's College Hospital NHS Foundation Trust, London, GBR.
Cureus. 2025 Jan 6;17(1):e77050. doi: 10.7759/cureus.77050. eCollection 2025 Jan.
Actinomycosis is a chronic, granulomatous infection caused by species, a group of anaerobic, gram-positive bacteria commonly found in the human oral cavity, gastrointestinal, and female genital tracts. Although it predominantly affects the cervicofacial region, rare manifestations such as gallbladder actinomycosis can occur. This report presents a case of gallbladder actinomycosis in a 61-year-old man who presented with a two-week history of right upper quadrant pain, jaundice, nausea, and vomiting. Imaging revealed biliary obstruction with common bile duct stones, leading to endoscopic retrograde cholangiopancreatography and subsequent laparoscopic cholecystectomy. Histopathological examination identified species, confirmed by Gram, PAS, and Grocott staining. While prolonged antibiotic therapy is the cornerstone of treatment, localized infections with complete surgical excision may not necessitate extended antibiotic use, as highlighted in this case.
放线菌病是一种由放线菌属引起的慢性肉芽肿性感染，放线菌属是一组厌氧的革兰氏阳性细菌，常见于人体口腔、胃肠道和女性生殖道。虽然它主要影响头颈部区域，但也可能出现罕见表现，如胆囊放线菌病。本报告介绍了一例61岁男性胆囊放线菌病病例，该患者有两周右上腹疼痛、黄疸、恶心和呕吐病史。影像学检查显示胆管梗阻伴胆总管结石，导致进行内镜逆行胰胆管造影术及随后的腹腔镜胆囊切除术。组织病理学检查通过革兰氏染色、过碘酸希夫染色和格罗科特染色鉴定出放线菌属。虽然长期抗生素治疗是治疗的基石，但如本病例所示，对于局部感染且已完全手术切除的情况，可能无需延长抗生素使用时间。
