Rastogi Deependra, Johri Prashant, Donelli Massimo, Kadry Seifedine, Khan Arfat Ahmad, Espa Giuseppe, Feraco Paola, Kim Jungeun
School of Computer Science and Engineering, IILM University, Greater Noida, Noida, 201306, UP, India.
SCSE, Galgotias University, Greater Noida, Noida, 203201, UP, India.
Sci Rep. 2025 Jan 9;15(1):1437. doi: 10.1038/s41598-024-84386-0.
The most prevalent form of malignant tumors that originate in the brain are known as gliomas. In order to diagnose, treat, and identify risk factors, it is crucial to have precise and resilient segmentation of the tumors, along with an estimation of the patients' overall survival rate. Therefore, we have introduced a deep learning approach that employs a combination of MRI scans to accurately segment brain tumors and predict survival in patients with gliomas. To ensure strong and reliable tumor segmentation, we employ 2D volumetric convolution neural network architectures that utilize a majority rule. This method helps to significantly decrease model bias and improve performance. Additionally, in order to predict survival rates, we extract radiomic features from the tumor regions that have been segmented, and then use a Deep Learning Inspired 3D replicator neural network to identify the most effective features. The model presented in this study was successful in segmenting brain tumors and predicting the outcome of enhancing tumor and real enhancing tumor. The model was evaluated using the BRATS2020 benchmarks dataset, and the obtained results are quite satisfactory and promising.
起源于大脑的最常见恶性肿瘤形式被称为胶质瘤。为了进行诊断、治疗并识别风险因素,对肿瘤进行精确且可靠的分割以及估计患者的总生存率至关重要。因此,我们引入了一种深度学习方法,该方法采用磁共振成像(MRI)扫描的组合来准确分割脑肿瘤并预测胶质瘤患者的生存率。为确保强大且可靠的肿瘤分割,我们采用利用多数规则的二维体积卷积神经网络架构。这种方法有助于显著降低模型偏差并提高性能。此外,为了预测生存率,我们从已分割的肿瘤区域提取放射组学特征,然后使用受深度学习启发的三维复制器神经网络来识别最有效的特征。本研究中提出的模型成功地分割了脑肿瘤并预测了增强肿瘤和实际增强肿瘤的结果。该模型使用BRATS2020基准数据集进行评估,所获得的结果相当令人满意且很有前景。