Thirunavukkarasu Eswaran, Aerva Manaswi Reddy, Chandrasekaran Baskaran, Maiya G Arun, Rao Chythra R
Department of Exercise and Sports Sciences, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Department of Physiotherapy, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Sci Rep. 2025 Jan 17;15(1):2329. doi: 10.1038/s41598-024-77827-3.
Prolonged sitting can negatively impact postprandial glucose levels and cognitive function. While short bouts of stair climbing are thought to mitigate these risks, the findings remain inconclusive. The present study aimed to explore the effects of stair climbing bouts on postprandial glucose and cognitive functions during prolonged sitting. Twenty-eight sedentary young adults (aged 20-30 years) underwent two intervention visits after standardised lunch for two hours: (1) STAIR: the participants climbed two flight of stairs for two minutes every 30 min; (2) SIT: the participants continued to sit. Blood glucose was measured using capillary finger prick method while attention function was measured using computer-based cognitive tests at baseline, end of 1st hour and 2nd hour. Significant interaction (F = 15.96, p < 0.001) was observed for conditions and time. During STAIR visit, significant changes in postprandial glucose at 1st hour (β = - 2.6 mmol/dl, p < 0.001) and 2nd hour (β = 3.0 mmol/dl, p < 0.001). No significant difference in the attention functions with time and conditions was observed. Stair climbing interruptions may serve as a feasible and effective countermeasure to high glycaemic variability or excursions that occur during prolonged sitting after postprandial hyperglycaemia.
长时间坐着会对餐后血糖水平和认知功能产生负面影响。虽然短时间爬楼梯被认为可以降低这些风险，但研究结果仍无定论。本研究旨在探讨爬楼梯对长时间坐着期间餐后血糖和认知功能的影响。28名久坐不动的年轻人（年龄在20 - 30岁之间）在标准化午餐后进行了两小时的两次干预访视：（1）爬楼梯组：参与者每30分钟爬两层楼梯，持续两分钟；（2）久坐组：参与者继续坐着。在基线、第1小时末和第2小时，使用毛细血管手指针刺法测量血糖，同时使用基于计算机的认知测试测量注意力功能。观察到条件和时间之间存在显著交互作用（F = 15.96，p < 0.001）。在爬楼梯访视期间，餐后第1小时（β = - 2.6 mmol/dl，p < 0.001）和第2小时（β = 3.0 mmol/dl，p < 0.001）的血糖有显著变化。未观察到注意力功能在时间和条件上的显著差异。爬楼梯中断可能是一种可行且有效的对策，可应对餐后高血糖后长时间坐着期间出现的高血糖变异性或血糖波动。
