住院儿童百日咳的严重程度——是否在下降？
The severity of whooping cough in hospitalised children--is it declining?
作者信息
Johnston I D, Anderson H R, Lambert H P
出版信息
J Hyg (Lond). 1985 Apr;94(2):151-61. doi: 10.1017/s0022172400061350.
Four hundred and sixty admissions for whooping cough to three hospitals between 1974-9 were reviewed. Many children had a long illness. More than half of them had severe or moderately severe coughing spasms and a quarter had pronounced feeding difficulties. The incidence of clinical pneumonia and convulsions was low and there were no deaths. The disease continues to be much more severe in infancy. There was some evidence that the disease declined in severity over the period studied. A number of factors including increased use of erythromycin may have contributed to this change.
对1974年至1979年间三家医院收治的460例百日咳患者进行了回顾性研究。许多儿童病程较长。其中一半以上有严重或中度严重的咳嗽痉挛，四分之一有明显的喂养困难。临床肺炎和惊厥的发生率较低，无死亡病例。该病在婴儿期仍然严重得多。有证据表明，在所研究的时期内，该病的严重程度有所下降。包括增加使用红霉素在内的一些因素可能促成了这一变化。
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