Robinson D A, Mandal B K, Ironside A G, Dunbar E M
Arch Dis Child. 1981 Sep;56(9):687-91. doi: 10.1136/adc.56.9.687.
In an attempt to determine the clinical severity and prognosis of children admitted to hospital with whooping cough, 127 patients were studied prospectively during a 12-month period. Clinical and laboratory criteria were used and the impression gained was that most cases were mild, although 3 children were dangerously ill and at least 30% had symptoms lasting 2 months or longer. There were no deaths, and no permanent sequelae were noted. The mean age of patients was higher than in other series, which might have accounted for the fairly low severity. Although there was some evidence of a decline in severity and mortality, whooping cough is still an unpleasant and protracted illness.
为了确定因百日咳入院儿童的临床严重程度和预后，在12个月期间对127例患者进行了前瞻性研究。采用了临床和实验室标准，得出的印象是大多数病例为轻症，尽管有3名儿童病情危急，且至少30%的患者症状持续2个月或更长时间。无死亡病例，也未发现永久性后遗症。患者的平均年龄高于其他系列研究中的患者，这可能是严重程度较低的原因。尽管有证据表明严重程度和死亡率有所下降，但百日咳仍然是一种令人不适且病程迁延的疾病。
