Jatsyk G V, Kuvaeva I B, Gribakin S G
Acta Paediatr Scand. 1985 Mar;74(2):246-9. doi: 10.1111/j.1651-2227.1985.tb10958.x.
Immunoglobulins A, M and G were measured in the milk of 20 nursing mothers at the beginning of lactation and simultaneously in the faeces of their children. The IgA level in the human milk was very high especially during the first week of lactation. After the start of breast-feeding IgA rapidly increased in the faeces, whereas IgG and IgM concentrations were consistently very low. In 74 normal full-term bottle-fed infants IgA appeared in the faeces at the age of 3-4 weeks but the level was significantly lower than the IgA level in breast-fed infants at the same age. Secretory IgA of human milk is stable and resistant to gastrointestinal juices and enzymes, thus giving passive immunological protection to the digestive tract of the newborn infant.
在20位哺乳期母亲泌乳初期的乳汁以及她们孩子的粪便中检测了免疫球蛋白A、M和G。人乳中的IgA水平非常高，尤其是在泌乳的第一周。开始母乳喂养后，粪便中的IgA迅速增加，而IgG和IgM的浓度一直很低。在74名正常足月人工喂养的婴儿中，IgA在3 - 4周龄时出现在粪便中，但水平明显低于同年龄母乳喂养婴儿的IgA水平。人乳中的分泌型IgA稳定，对胃肠液和酶具有抵抗力，从而为新生儿的消化道提供被动免疫保护。
