Yang Yang, Liu Zhong
Department of Orthopedics, Xiangtan Central Hospital, Xiangtan, China.
Front Public Health. 2025 Feb 6;13:1455726. doi: 10.3389/fpubh.2025.1455726. eCollection 2025.
Gout is a significant global health issue, particularly among adults aged 70 and above. Understanding its epidemiological evolution and associated factors is crucial for guiding interventions and improving management.
This study analyzed data from the Global Burden of Disease study to assess the prevalence and trends of gout among adults aged 70 and above from 1990 to 2019. We evaluated temporal trends and regional disparities by calculating the estimated annual percentage change (EAPCs).
Globally, the number of older adults individuals affected by gout increased from 5,316,210 cases in 1990 to 15,666,063 cases in 2019. It is noteworthy that the global burden of gout among the older adults continued to rise from 1990 to 2019, with an EAPC of 1.17 (95% CI: 1.02 to 1.32). In 2019, the prevalence rates among individuals aged 70-74, 75-79, 80-84, and 85 and above were 3,121.31 per 100,000, 3,437.17 per 100,000, 3,592.38 per 100,000, and 3,726.91 per 100,000, respectively. The regions with the highest prevalence rates of gout in 2019 were Australasia, High-income North America, and Southern Latin America, with rates of 8,500.73, 8,351.33, and 4,666.87 per 100,000, respectively. At the national level, some developed countries such as New Zealand, the United States of America, and Australia had the highest prevalence rates, reaching 8,893.74, 8,508.06, and 8,427.94 per 100,000, respectively. It is noteworthy that regions with higher levels of Socio-Demographic Index tended to have relatively higher burden of gout among the older adults, and the prevalence rates varied across different regions and age groups.
The study underscores the persistent burden of gout among the older adults, emphasizing the need for targeted interventions to address this issue and improve public health outcomes in this demographic.
痛风是一个重大的全球健康问题，在70岁及以上的成年人中尤为突出。了解其流行病学演变及相关因素对于指导干预措施和改善管理至关重要。
本研究分析了全球疾病负担研究的数据，以评估1990年至2019年70岁及以上成年人中痛风的患病率和趋势。我们通过计算估计的年百分比变化（EAPC）来评估时间趋势和地区差异。
在全球范围内，受痛风影响的老年人数量从1990年的5316210例增加到2019年的15666063例。值得注意的是，1990年至2019年期间，老年人中痛风的全球负担持续上升，EAPC为1.17（95%CI：1.02至1.32）。2019年，70 - 74岁、75 - 79岁、80 - 84岁以及85岁及以上人群的患病率分别为每10万人3121.31例、3437.17例、3592.38例和3726.91例。2019年痛风患病率最高的地区是澳大拉西亚、高收入北美洲和拉丁美洲南部，患病率分别为每10万人8500.73例、8351.33例和4666.87例。在国家层面，一些发达国家如新西兰、美利坚合众国和澳大利亚的患病率最高，分别达到每10万人8893.74例、8508.06例和8427.94例。值得注意的是，社会人口指数较高的地区，老年人中痛风负担往往相对较高，且患病率在不同地区和年龄组之间存在差异。
该研究强调了老年人中痛风负担的持续性，强调需要采取针对性干预措施来解决这一问题，并改善这一人群的公共卫生结果。
