高强度体重间歇训练与呼吸锻炼相结合对正常体重的中年高血压成年人心脏代谢健康的影响。
Impact of combined high-intensity bodyweight interval training and breathing exercise on cardiometabolic health in normal-weight middle-aged adults with hypertension.
作者信息
Herawati Isnaini, Mat Ludin Arimi Fitri, Ishak Ismarulyusda, Mutalazimah Mutalazimah, Farah Nor M F
机构信息
Center for Healthy Ageing and Wellness, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, 50300, Malaysia.
Faculty of Health Sciences, Universitas Muhammadiyah Surakarta, J. A.Yani Tromol Pos 1 Pabelan Kartasura, Surakarta, 57102, Indonesia.
出版信息
BMC Public Health. 2025 Mar 11;25(1):962. doi: 10.1186/s12889-025-22139-y.
BACKGROUND
High-intensity interval training and breathing exercises alone have well-documented health benefits in people with hypertension. This study aimed to investigated the effects of combining the two methods on physical health among adults with hypertension.
METHODS
Ninety-six adults (59.4 ± 9.1 years; 84% female; BMI 22.7 ± 1.6 kg/m) with hypertension were randomized into one of four groups: Breathing Exercise (BE), High-Intensity Bodyweight Interval Training (HIBIT), Combined Exercise (CE), or a Non-Exercise Control (CON) group. The intervention lasted 10 weeks, with all exercise groups having the same total training time of 3 days per week (BE: 30 min/day; HIBIT: 60 min/day; CE: BE 30 min/day plus HIBIT 60 min/day). Resting heart rate, resting blood pressure, hand grip strength, cardiorespiratory fitness assessed using 6-Minute Walking Test (6MWT) and blood lipids were measured pre- and post-intervention.
RESULTS
The BE group showed the greatest reduction in systolic blood pressure (SBP) compared to CON, although differences among the exercise groups were not statistically significant. The increase in 6MWT values in the combined exercise group differed significantly compared to the other three groups (p = 0.000 and effect size = 0.296). The combined exercise group showed significant reductions in total cholesterol, LDL and triglyceride levels compared to the control group. The average reduction in total cholesterol levels was 20.8 mg/dL (95% C: -41.9 - 0.4) with an effect size of 0.103. Meanwhile, the decrease in LDL and triglyceride levels was 20.1 mg/dL (95% CI: -37.6--2.5; p = 0.014) and -40.4 mg/dL (95% CI: -82.1-1.3; p = 0.04) with effect sizes of 0.118 and 0.101.
CONCLUSIONS
In conclusion combined exercise for 10 weeks could lower systolic and diastolic blood pressure, increase CRF, and improved lipid profile. As a clinical implication, the results of this study can be an alternative or complementary approach to treatment for hypertension, potentially reducing the need for medications and their associated side effects.
TRIAL REGISTRATION
TCTR20230707003 ( http://www.
CLINICALTRIALS
in.th/ ) registered on 28 January 2023.
背景
高强度间歇训练和单独的呼吸练习对高血压患者的健康益处已有充分记录。本研究旨在调查将这两种方法结合对成年高血压患者身体健康的影响。
方法
96名患有高血压的成年人（年龄59.4±9.1岁；84%为女性；BMI 22.7±1.6kg/m）被随机分为四组之一：呼吸练习组（BE）、高强度体重间歇训练组（HIBIT）、联合运动组（CE）或非运动对照组（CON）。干预持续10周，所有运动组每周总训练时间相同，均为3天（BE：每天30分钟；HIBIT：每天60分钟；CE：BE每天30分钟加HIBIT每天60分钟）。在干预前后测量静息心率、静息血压、握力、使用6分钟步行试验（6MWT）评估的心肺适能和血脂。
结果
与对照组相比，BE组收缩压（SBP）下降幅度最大，尽管运动组之间的差异无统计学意义。联合运动组6MWT值的增加与其他三组相比有显著差异（p = 0.000，效应量 = 0.296）。与对照组相比，联合运动组的总胆固醇、低密度脂蛋白和甘油三酯水平显著降低。总胆固醇水平平均降低20.8mg/dL（95%可信区间：-41.9 - 0.4），效应量为0.103。同时，低密度脂蛋白和甘油三酯水平分别降低20.1mg/dL（95%可信区间：-37.6--2.5；p = 0.014）和-40.4mg/dL（95%可信区间：-82.1-1.3；p = 0.04），效应量分别为0.118和0.101。
结论
总之，10周的联合运动可以降低收缩压和舒张压，提高心肺适能，并改善血脂状况。作为临床意义，本研究结果可以作为高血压治疗的一种替代或补充方法，并可能减少药物需求及其相关副作用。
试验注册
TCTR20230707003（http://www.CLINICALTRIALS:in.th/）于2023年1月28日注册。
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