McLintock Cameron, McKelvie James, Niyazmand Hamed, Uprety Samir
Department of Ophthalmology, Princess Alexandra hospital, Brisbane, QLD, Australia.
Faculty of Medicine, University of Queensland, 199 Ipswich Road, Woolloongabba, Brisbane, QLD, 4102, Australia.
BMC Ophthalmol. 2025 Mar 12;25(1):127. doi: 10.1186/s12886-025-03916-0.
This study evaluated the agreement of the ocular parameters obtained with the two optical biometers, the IOLMaster 700 and the Galilei G6 Lens Professional.
A comparative prospective study was conducted on 159 eyes of 91 adult patients using the IOLMaster 700 and Galilei G6 devices by a single examiner. Agreement between ocular biometric parameters: white-to-white (WTW) distance, keratometry (flat (K1) and steep (K2), mean (Km)) of anterior, posterior, and total corneal surfaces, central corneal thickness (CCT), anterior chamber depth (ACD), and axial length (AL) were assessed using Bland-Altman analysis. Keratometry measurements were further transformed into power vector components J0 and J45 for astigmatism analysis. Clinically significant differences were defined as deviations in biometric parameters translating to differences of 0.25 D or more in refractive outcomes.
Statistically and clinically significant difference was identified for ACD (mean difference: -0.15 mm), posterior corneal metrics: K1 (0.39 D), K2 (0.42 D), Km (0.41 D) and J0 (0.05 D) and total corneal metrics: K1 (0.95 D), K2 (0.91 D), Km (0.93 D) and J0 (0.13 D). No significant differences were found for J45 components of posterior and total K, WTW, CCT, and AL measurements.
The difference in measurements of anterior chamber depth (ACD), posterior K, and total K metrics are clinically significant making the two devices are clinically significant and not interchangeable. These variation in metrics can impact the refractive outcomes of refractive and cataract surgery with toric IOLs.
本研究评估了使用两种光学生物测量仪IOLMaster 700和Galilei G6 Lens Professional获得的眼部参数的一致性。
由一名检查者使用IOLMaster 700和Galilei G6设备,对91例成年患者的159只眼睛进行了一项比较性前瞻性研究。使用Bland-Altman分析评估眼部生物测量参数之间的一致性:白对白(WTW)距离、前、后和全角膜表面的角膜曲率(平坦(K1)和陡峭(K2),平均值(Km))、中央角膜厚度(CCT)、前房深度(ACD)和眼轴长度(AL)。角膜曲率测量值进一步转换为散光分析的屈光力矢量分量J0和J45。临床显著差异定义为生物测量参数的偏差转化为屈光结果差异0.25 D或更大。
在ACD(平均差异:-0.15 mm)、后角膜指标:K1(0.39 D)、K2(0.42 D)、Km(0.41 D)和J0(0.05 D)以及全角膜指标:K1(0.95 D)、K2(0.91 D)、Km(0.93 D)和J0(0.13 D)方面发现了统计学和临床显著差异。后角膜和全角膜K的J45分量、WTW、CCT和AL测量值未发现显著差异。
前房深度(ACD)、后角膜K和全角膜K测量值的差异具有临床意义,这使得这两种设备具有临床意义且不可互换。这些指标的变化会影响使用散光型人工晶状体的屈光手术和白内障手术的屈光结果。