Lang Zhigang, Zhang Xu, Liang Yuxiang
Zhigang Lang Department of Orthopedics, Sichuan Orthopedic Hospital, Chengdu 610041, Sichuan, China.
Xu Zhang Department of Orthopedics, Sichuan Orthopedic Hospital, Chengdu 610041, Sichuan, China.
Pak J Med Sci. 2025 Mar;41(3):792-797. doi: 10.12669/pjms.41.3.9872.
To explore the clinical efficacy of antibiotic-loaded bone cement in the treatment of lower limb soft tissue infection.
A retrospective analysis was carried out on 40 patients with lower limb soft tissue infection who were admitted to Sichuan Orthopedic Hospital from January 1, 2022 to December 1, 2023. The enrolled patients were divided into two groups according to different therapies, including the bone cement treatment (the study group) group and the conventional treatment group (the control group), with 20 cases in each group. Further comparison was made on the number of operations, wound healing time, Grade-A wound healing rate, recurrence rate, and recovery rate of inflammatory indicators between the two groups.
Patients in both groups were followed up, and there was no statistically significant difference in the number of operations between the two groups (P>0.05). The study group had shorter wound healing time (P<0.05), higher Grade-A wound healing rate (P<0.05), lower recurrence rate (P<0.05), and higher normal rate of inflammatory indicators (P<0.05) than those in the control group.
Antibiotic-loaded bone cement showed a clear effect on treating lower limb soft tissue infection, with good wound healing and low recurrence rate.
探讨载抗生素骨水泥治疗下肢软组织感染的临床疗效。
对2022年1月1日至2023年12月1日收治于四川省骨科医院的40例下肢软组织感染患者进行回顾性分析。将入选患者根据不同治疗方法分为两组，包括骨水泥治疗组（研究组）和传统治疗组（对照组），每组20例。进一步比较两组的手术次数、伤口愈合时间、甲级愈合率、复发率及炎症指标恢复率。
两组患者均获随访，两组手术次数比较差异无统计学意义（P>0.05）。研究组伤口愈合时间短于对照组（P<0.05），甲级愈合率高于对照组（P<0.05），复发率低于对照组（P<0.05），炎症指标恢复正常率高于对照组（P<0.05）。
载抗生素骨水泥治疗下肢软组织感染效果明显，伤口愈合良好，复发率低。
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