人泌尿生殖道分泌物对淋病奈瑟菌黏附的抑制作用。
Inhibition of adherence of Neisseria gonorrhoeae by human genital secretions.
作者信息
Tramont E C
出版信息
J Clin Invest. 1977 Jan;59(1):117-24. doi: 10.1172/JCI108608.
Abstract
Local genital antibodies to the infecting strains of Neisseria gonorrhoeae were demonstrated by indirect immunofluorescence (binding antibody) and by their ability to inhibit the attachment of gonococci to epithelial cells (functional antibody). Both IgG and IgA classes of immunoglobulin were involved, and the IgA component were primarily of a secreting (11S) nature. The ability of local genital antibody to inhibit attachment appears to persist for at least a short period of time and to be relatively strain specific.
摘要
通过间接免疫荧光法（结合抗体）以及其抑制淋球菌附着于上皮细胞的能力（功能性抗体），证实了针对淋病奈瑟菌感染菌株的局部生殖器抗体的存在。免疫球蛋白的IgG和IgA类别均参与其中，且IgA成分主要具有分泌性（11S）性质。局部生殖器抗体抑制附着的能力似乎至少在短时间内持续存在，并且具有相对的菌株特异性。
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