Kinuta Minako, Hisamatsu Takashi, Taniguchi Kaori, Fukuda Mari, Nakahata Noriko, Kanda Hideyuki
Department of Public Health, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Department of Environmental Medicine and Public Health, Izumo, Shimane University Faculty of Medicine, Izumo, Japan.
J Hum Hypertens. 2025 Apr 3. doi: 10.1038/s41371-025-01014-8.
Few studies have examined the association of objectively measured habitual physical activity (PA) and sedentary behavior with out-of-office blood pressure (BP). We investigated the associations of objectively measured PA intensity time, sedentary time, and step count with at-home BP. Using accelerometer-recorded PA indices and self-measured BP in 368 participants (mean age, 53.8 years; 58.7% women), we analyzed 115,575 records of each parameter between May 2019 and April 2024. PA intensities were categorized as light (2.0-2.9 metabolic equivalents [METs]); moderate (3.0-5.9 METs); vigorous (≥6.0 METs), or sedentary (<2.0 METs): the median [interquartile ranges] for these variables was 188 [146-232], 83 [59-114], 1 [0-2], 501 [428-579] minutes, respectively, and for step count, was 6040 [4164-8457]. Means [standard deviations] for systolic and diastolic BP were 116.4 [14.2] and 75.2 [9.3] mmHg, respectively. A mixed-effect model adjusted for possible confounders showed that 1-h longer in vigorous PA was associated with lower systolic and diastolic BP (-1.69 and -1.09 mmHg, respectively). A 1000-step increase in step count was associated with lower systolic and diastolic BP (-0.05 and -0.02 mmHg, respectively). Associations were more pronounced among men and participants aged <60 years. Sedentary time was positively associated with BP in men and participants aged <60 years, but inversely associated with BP in women and participants aged ≥60 years. Our findings suggest that more PA and less sedentary behavior were associated with BP reduction, particularly among men and participants aged <60 years. However, the clinical relevance of this effect remains uncertain because of its modest magnitude.
很少有研究探讨客观测量的习惯性身体活动（PA）和久坐行为与非工作时间血压（BP）之间的关联。我们调查了客观测量的PA强度时间、久坐时间和步数与家庭血压之间的关联。利用加速度计记录的PA指标和368名参与者（平均年龄53.8岁；58.7%为女性）的自我测量血压，我们分析了2019年5月至2024年4月期间每个参数的115575条记录。PA强度分为轻度（2.0-2.9代谢当量[METs]）；中度（3.0-5.9 METs）；剧烈（≥6.0 METs）或久坐（<2.0 METs）：这些变量的中位数[四分位间距]分别为188[146-232]、83[59-114]、1[0-2]、501[428-579]分钟，步数的中位数为6040[从4164-8457]。收缩压和舒张压的均值[标准差]分别为116.4[14.2]和75.2[9.3]mmHg。调整可能的混杂因素后的混合效应模型显示，剧烈PA每增加1小时，收缩压和舒张压分别降低（-1.69和-1.09 mmHg）。步数每增加1000步，收缩压和舒张压分别降低（-0.05和-0.02 mmHg）。在男性和年龄<60岁的参与者中，这种关联更为明显。久坐时间在男性和年龄<60岁的参与者中与血压呈正相关，但在女性和年龄≥60岁的参与者中与血压呈负相关。我们的研究结果表明，更多的PA和更少的久坐行为与血压降低有关，尤其是在男性和年龄<60岁的参与者中。然而，由于这种影响的程度较小，其临床相关性仍不确定。
