Sadeghi Atefeh, Nazarali Parvaneh, Alizadeh Rostam, Ceylan Halil İbrahim, Nobari Hadi
Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Allameh Tabataba'i University, Tehran, Iran.
Department of Exercise Physiology, Faculty of Sports Sciences, Alzahra University, Tehran, Iran.
J Diabetes Metab Disord. 2025 Apr 5;24(1):96. doi: 10.1007/s40200-025-01608-6. eCollection 2025 Jun.
This study evaluated the effects of maximal and submaximal exercise training on serum levels of Asprosin, insulin resistance, and body composition in overweight and obese women.
30 overweight/obese women voluntarily participated in the study and were then randomly divided into control, submaximal, and maximal groups. A treadmill high-intensity exercise protocol was applied to MG non-consecutive three days a week for 8 weeks, in four 4-min intervals with an intensity of 70 to 95% of maximum heart rate (HRmax) with 3-min active recovery intervals. SMG performed a moderate-intensity exercise protocol of approximately 25 to 35 min at the treadmill at 50-70% of HRmax non-consecutive days three days per week for 8 weeks. The CG continued their daily routine activities. Anthropometric and body composition measurements such as body weight, height, BMI, and waist-hip ratio (WHR) were performed before and after the 8-week training period. Fasting blood glucose (FGB), insulin, insulin resistance (HOMA-IR), and serum asprosin levels were also measured.
Post-training, there were significant main effects of time and a group-by-time interaction for all body composition and performance variables ( < 0.001). Post hoc analysis revealed that body mass, BMI, WHR, FBG, insulin, HOMA-IR, and serum asprosin were significantly reduced after 8 8-week training program.
The present study showed that maximal and submaximal exercise protocols effectively improved body composition, insulin sensitivity, resistance, and reduced asprosin level. It has been concluded that these effects are more pronounced, especially after maximal exercise protocols.
本研究评估了最大强度和次最大强度运动训练对超重和肥胖女性血清阿朴脂蛋白水平、胰岛素抵抗和身体成分的影响。
30名超重/肥胖女性自愿参与本研究，随后被随机分为对照组、次最大强度组和最大强度组。对最大强度组（MG）采用跑步机高强度运动方案，每周非连续三天，共8周，每次4分钟，强度为最大心率（HRmax）的70%至95%，中间有3分钟的主动恢复间隔。次最大强度组（SMG）采用中等强度运动方案，每周非连续三天，在跑步机上以HRmax的50%-70%进行约25至35分钟的运动，共8周。对照组（CG）继续其日常活动。在为期8周的训练期前后，进行了人体测量和身体成分测量，如体重、身高、体重指数（BMI）和腰臀比（WHR）。还测量了空腹血糖（FGB）、胰岛素、胰岛素抵抗（HOMA-IR）和血清阿朴脂蛋白水平。
训练后，所有身体成分和性能变量在时间上有显著的主效应，且存在组间与时间的交互作用（<0.001）。事后分析显示，经过8周的训练计划后，体重、BMI、WHR、FGB、胰岛素、HOMA-IR和血清阿朴脂蛋白均显著降低。
本研究表明，最大强度和次最大强度运动方案能有效改善身体成分、胰岛素敏感性、抵抗能力，并降低阿朴脂蛋白水平。得出的结论是，这些效果更为显著，尤其是在最大强度运动方案之后。
