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基于残差网络(Resnet)和双向门控循环单元(GRU)的失神发作检测方法

Detection method of absence seizures based on Resnet and bidirectional GRU.

作者信息

Li Lijun, Zhang Hengxing, Liu Xiaomei, Li Jie, Li Lei, Liu Dan, Min Jieqing, Zhu Ping, Xia Huan, Wang Shangkun, Wang Li

机构信息

Kunming children's hospital, Kunming, 650000, China.

Zhengzhou Zoneyet Technology Corp.,Ltd, Zhengzhou, 450000, China.

出版信息

Acta Epileptol. 2023 Mar 1;5(1):7. doi: 10.1186/s42494-022-00117-w.

Abstract

BACKGROUND

Epilepsy is a common chronic neurological disease. Its repeated seizure attacks have a great negative impact on patients' physical and mental health. The diagnosis of epilepsy mainly depends on electroencephalogram (EEG) signals detection and analysis. There are two main EEG signals detection methods for epilepsy. One is the detection based on abnormal waveform, the other is the analysis of EEG signals based on the traditional machine learning. The feature extraction method of the traditional machine learning is difficult to capture the high-dimension information between adjacent sequences.

METHODS

In this paper, redundant information was removed from the data by Gaussian filtering, downsampling, and short-time Fourier transform. Convolutional Neural Networks (CNN) was used to extract the high-dimensional features of the preprocessed data, and then Gate Recurrent Unit (GRU) was used to combine the sequence information before and after, to fully integrate the adjacent information EEG signals and improve the accuracy of the model detection.

RESULTS

Four models were designed and compared. The experimental results showed that the prediction model based on deep residual network and bidirectional GRU had the best effect, and the test accuracy of the absence epilepsy test set reached 92%.

CONCLUSIONS

The prediction time of the network is only 10 sec when predicting four-hour EEG signals. It can be effectively used in EEG software to provide reference for doctors in EEG analysis and save doctors' time, which has great practical value.

摘要

背景

癫痫是一种常见的慢性神经系统疾病。其反复发作对患者的身心健康有很大的负面影响。癫痫的诊断主要依赖于脑电图(EEG)信号的检测与分析。癫痫的脑电图信号检测方法主要有两种。一种是基于异常波形的检测,另一种是基于传统机器学习的脑电图信号分析。传统机器学习的特征提取方法难以捕捉相邻序列之间的高维信息。

方法

本文通过高斯滤波、下采样和短时傅里叶变换对数据进行冗余信息去除。利用卷积神经网络(CNN)提取预处理后数据的高维特征,然后使用门控循环单元(GRU)对前后序列信息进行融合,充分整合脑电图信号的相邻信息,提高模型检测的准确性。

结果

设计并比较了四种模型。实验结果表明,基于深度残差网络和双向GRU的预测模型效果最佳,失神癫痫测试集的测试准确率达到92%。

结论

该网络在预测4小时脑电图信号时预测时间仅为10秒。它可以有效地应用于脑电图软件中,为医生进行脑电图分析提供参考,节省医生时间,具有很大的实用价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01aa/11960378/898a6bde1c88/42494_2022_117_Fig1_HTML.jpg

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