Smits P, Thien T, Van 't Laar A
Br J Clin Pharmacol. 1985 Jun;19(6):852-4. doi: 10.1111/j.1365-2125.1985.tb02729.x.
In a single-blind study the effects of drinking two cups of regular or decaffeinated coffee on blood pressure, heart rate, forearm blood flow and plasma concentrations of caffeine, renin and catecholamines were studied in 12 normotensive subjects. Drinking regular coffee led to a rise of blood pressure, a fall of heart rate and an increase of plasma catecholamines. Decaffeinated coffee induced a smaller increase of diastolic blood pressure without changing other parameters. This study shows that the cardiovascular effects of drinking coffee are mainly the result of its caffeine content.
在一项单盲研究中,对12名血压正常的受试者饮用两杯普通咖啡或脱咖啡因咖啡后对血压、心率、前臂血流量以及咖啡因、肾素和儿茶酚胺的血浆浓度的影响进行了研究。饮用普通咖啡导致血压升高、心率下降以及血浆儿茶酚胺增加。脱咖啡因咖啡使舒张压有较小幅度的升高,而其他参数未发生变化。这项研究表明,喝咖啡对心血管系统的影响主要是其咖啡因含量所致。