Yang Jin, Qian Dangwei, Wang Gangwei, Yang Shangdong
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.
State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
Molecules. 2025 Mar 31;30(7):1564. doi: 10.3390/molecules30071564.
A facile and efficient method for synthesizing diarylphosphinates from alcohols and aryl halides, using stable, green, and readily available sodium hypophosphite as a phosphorus source, is disclosed herein for the first time. This method offers high-efficiency and excellent functional group tolerance, providing a straightforward approach to synthesizing a broad range of diarylphosphinates from green starting materials with moderate to excellent yields.
本文首次公开了一种简便高效的方法，该方法使用稳定、绿色且易于获得的次磷酸钠作为磷源，从醇类和芳基卤化物合成二芳基次膦酸酯。该方法具有高效性和出色的官能团耐受性，提供了一种直接的途径，能够以中等至优异的产率从绿色起始原料合成多种二芳基次膦酸酯。
