Martin D G, Ferguson E W, Wigutoff S, Gawne T, Schoomaker E B
J Appl Physiol (1985). 1985 Aug;59(2):348-53. doi: 10.1152/jappl.1985.59.2.348.
To assess whether the rheological properties of blood might be altered by exercise, we measured whole blood viscosity, plasma viscosity, and its components in healthy female subjects before, immediately after, and 1 h after maximal upright exercise using the Bruce graded exercise protocol. Forty-seven female subjects (15 sedentary, 14 who ran 5-15 miles/wk, and 18 who ran greater than 50 miles/wk), ages 18-43 yr, were evaluated. Whole blood viscosity, measured with a cone and plate viscometer, increased an average of 12.6% with exercise. The increase was greater than can be attributed to the observed 8.9% increase in hematocrit alone due to a coincident increase in plasma protein concentration. However, plasma viscosity did not rise to the degree expected, likely due to a disproportionate observed loss of fibrinogen from the protein pool. These changes were independent of conditioning level or aerobic capacity. In this cross-sectional study, there appears to be no adaptive adjustment in females to physical conditioning that results in changes in blood viscosity.
为了评估运动是否会改变血液的流变学特性,我们使用布鲁斯分级运动方案,在健康女性受试者进行最大强度直立运动前、运动后即刻以及运动后1小时,测量了全血粘度、血浆粘度及其成分。对47名年龄在18 - 43岁的女性受试者(15名久坐不动者、14名每周跑步5 - 15英里者以及18名每周跑步超过50英里者)进行了评估。使用锥板粘度计测量的全血粘度在运动后平均增加了12.6%。这种增加幅度大于仅因血细胞比容观察到的8.9%的增加幅度,这是由于血浆蛋白浓度同时增加所致。然而,血浆粘度并未上升到预期程度,可能是由于观察到蛋白池中纤维蛋白原不成比例地减少。这些变化与身体状况或有氧能力无关。在这项横断面研究中,女性似乎没有因身体锻炼而产生适应性调整,从而导致血液粘度发生变化。