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耐力训练的女性受试者和久坐不动的女性受试者在最大运动时的血液粘度反应。

Blood viscosity responses to maximal exercise in endurance-trained and sedentary female subjects.

作者信息

Martin D G, Ferguson E W, Wigutoff S, Gawne T, Schoomaker E B

出版信息

J Appl Physiol (1985). 1985 Aug;59(2):348-53. doi: 10.1152/jappl.1985.59.2.348.

DOI:10.1152/jappl.1985.59.2.348
PMID:4030588
Abstract

To assess whether the rheological properties of blood might be altered by exercise, we measured whole blood viscosity, plasma viscosity, and its components in healthy female subjects before, immediately after, and 1 h after maximal upright exercise using the Bruce graded exercise protocol. Forty-seven female subjects (15 sedentary, 14 who ran 5-15 miles/wk, and 18 who ran greater than 50 miles/wk), ages 18-43 yr, were evaluated. Whole blood viscosity, measured with a cone and plate viscometer, increased an average of 12.6% with exercise. The increase was greater than can be attributed to the observed 8.9% increase in hematocrit alone due to a coincident increase in plasma protein concentration. However, plasma viscosity did not rise to the degree expected, likely due to a disproportionate observed loss of fibrinogen from the protein pool. These changes were independent of conditioning level or aerobic capacity. In this cross-sectional study, there appears to be no adaptive adjustment in females to physical conditioning that results in changes in blood viscosity.

摘要

为了评估运动是否会改变血液的流变学特性,我们使用布鲁斯分级运动方案,在健康女性受试者进行最大强度直立运动前、运动后即刻以及运动后1小时,测量了全血粘度、血浆粘度及其成分。对47名年龄在18 - 43岁的女性受试者(15名久坐不动者、14名每周跑步5 - 15英里者以及18名每周跑步超过50英里者)进行了评估。使用锥板粘度计测量的全血粘度在运动后平均增加了12.6%。这种增加幅度大于仅因血细胞比容观察到的8.9%的增加幅度,这是由于血浆蛋白浓度同时增加所致。然而,血浆粘度并未上升到预期程度,可能是由于观察到蛋白池中纤维蛋白原不成比例地减少。这些变化与身体状况或有氧能力无关。在这项横断面研究中,女性似乎没有因身体锻炼而产生适应性调整,从而导致血液粘度发生变化。

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