Tan Yufei, Xu Yanan, Liang Die, Zhang Yan, Cai Wenzhi, Ren Wei, Chen Ling
Department of Nursing, Shenzhen Hospital, Southern Medical University, Shenzhen, 518101, Guangdong, PR China.
School of Nursing, Southern Medical University, Guangzhou, 510515, Guangdong, PR China.
BMC Pediatr. 2025 May 10;25(1):370. doi: 10.1186/s12887-025-05706-5.
Lower urinary tract symptoms (LUTS) are common in pediatric patients and significantly affect children's well-being and family-related quality of life. However, no validated Chinese assessment tool for LUTS exists. This study aimed to develop and validate a Chinese version of the International Consultation on Incontinence Questionnaire-Pediatric Lower Urinary Tract Symptoms (ICIQ-CLUTS).
The ICIQ-CLUTS was translated following the Beaton cross-cultural adaptation guidelines. A total of 192 children with and without LUTS and their parents were enrolled between June and October 2024. Psychometric evaluation was performed using multiple approaches. Reliability was assessed using Cronbach's alpha coefficient for internal consistency. Validity was assessed by expert content review and exploratory factor analysis. Clinical diagnoses were made using standardized assessment protocols including medical history, physical examination, and laboratory tests (urinalysis and uroflowmetry) based on the International Children's Continence Society (ICCS) criteria. Using these clinical diagnoses as the reference standard, the diagnostic accuracy was evaluated using receiver operating characteristic (ROC) curve analysis.
The study included 192 participants (70.8% male) divided into two age groups: 5-9 years (n = 139) and 10-14 years (n = 53). The Chinese ICIQ-CLUTS showed acceptable internal consistency (Cronbach's alpha = 0.718 for children's version; 0.706 for parents' version) and distinct factor structure. The diagnoses encompassed various LUTS manifestations including monosymptomatic nocturnal enuresis (MNE), non-monosymptomatic nocturnal enuresis (NMNE), and overactive bladder (OAB). Both versions exhibited high diagnostic accuracy (AUC = 0.948 for children's version; 0.933 for parents' version), with superior performance observed in the 10-14-year age group (AUC = 0.963 and 0.960, respectively). The optimal cut-off points were 13.5 for both versions, with sensitivity of 0.90 and specificity of 0.86 for the children's version, and sensitivity of 0.89 and specificity of 0.85 for the parents' version.
The Chinese version of ICIQ-CLUTS shows good psychometric properties and diagnostic accuracy, making it a useful screening tool for pediatric LUTS in Chinese-speaking populations.
下尿路症状（LUTS）在儿科患者中很常见，会显著影响儿童的幸福感和家庭相关生活质量。然而，目前尚无经过验证的中文版LUTS评估工具。本研究旨在开发并验证中文版的《国际尿失禁咨询委员会-儿科下尿路症状问卷》（ICIQ-CLUTS）。
按照比顿跨文化适应指南对ICIQ-CLUTS进行翻译。2024年6月至10月期间，共招募了192名有或无LUTS的儿童及其父母。采用多种方法进行心理测量评估。使用克朗巴赫α系数评估内部一致性以评估信度。通过专家内容审查和探索性因素分析评估效度。根据国际儿童尿控协会（ICCS）标准，采用包括病史、体格检查和实验室检查（尿液分析和尿流率测定）在内的标准化评估方案进行临床诊断。以这些临床诊断作为参考标准，采用受试者工作特征（ROC）曲线分析评估诊断准确性。
该研究纳入了192名参与者（70.8%为男性），分为两个年龄组：5-9岁（n = 139）和10-14岁（n = 53）。中文版ICIQ-CLUTS显示出可接受的内部一致性（儿童版克朗巴赫α系数 = 0.718；父母版克朗巴赫α系数 = 0.706）和独特的因素结构。诊断涵盖了各种LUTS表现，包括单症状性夜间遗尿症（MNE）、非单症状性夜间遗尿症（NMNE）和膀胱过度活动症（OAB）。两个版本均显示出较高的诊断准确性（儿童版AUC = 0.948；父母版AUC = 0.933），在10-14岁年龄组中表现更优（AUC分别为0.963和0.960）。两个版本的最佳截断点均为13.5，儿童版的灵敏度为0.90，特异度为0.86，父母版的灵敏度为0.89，特异度为0.85。
中文版ICIQ-CLUTS显示出良好的心理测量特性和诊断准确性，使其成为华语人群儿科LUTS的有用筛查工具。
