Atkinson Barry, Gould Susan, Nicholls Ian, Manzoor Khanzadi Nazneen, Smith Jack, Hindle Andrew J, Tunbridge Anne J, Cole Joby, Collini Paul, Alonso Alejandra, O'Hara Geraldine, Tuudah Cecilia, Otter Jonathan A, Hack Berkin, Taylor Caroline, Pottage Thomas, Fletcher Tom, Dunning Jake
NIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Liverpool, United Kingdom.
Diagnostics and Pathogen Characterisation, UK Health Security Agency, Porton Down, Salisbury, United Kingdom.
Euro Surveill. 2025 May;30(19). doi: 10.2807/1560-7917.ES.2025.30.19.2500288.
Air and surface sampling was performed in isolation rooms of seven patients with clade Ib mpox admitted to high consequence infectious disease centres in the United Kingdom. We detected monkeypox virus (MPXV) DNA in 66/90 surfaces samples and 1/14 air samples; replication competent MPXV was identified in 4/21 surface samples selected for viral isolation. These findings demonstrate that viable clade Ib MPXV contamination can occur during treatment of clade Ib mpox patients reinforcing the importance of infection prevention and control measures.
对英国高后果传染病中心收治的7例Ib分支猴痘患者的隔离病房进行了空气和表面采样。我们在90份表面样本中的66份以及14份空气样本中的1份中检测到猴痘病毒（MPXV）DNA；在选取用于病毒分离的21份表面样本中的4份中鉴定出具有复制能力的MPXV。这些发现表明，在治疗Ib分支猴痘患者期间可能会发生有活力的Ib分支MPXV污染，这强化了感染预防和控制措施的重要性。
