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猴痘病毒在无生命表面的稳定性和失活。

Stability and Inactivation of Monkeypox Virus on Inanimate Surfaces.

机构信息

Department for Molecular and Medical Virology, Ruhr University Bochum, Bochum.

European Virus Bioinformatics Center, Jena.

出版信息

J Infect Dis. 2023 Nov 2;228(9):1227-1230. doi: 10.1093/infdis/jiad127.

DOI:10.1093/infdis/jiad127
PMID:37129073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10629702/
Abstract

The spread of nonzoonotic monkeypox virus (MPXV) infections necessitates the reevaluation of hygiene measures. To date, only limited data are available on MPXV surface stability. Here, we evaluate the stability of infectious MPXV on stainless steel stored at different temperatures, while using different interfering substances to mimic environmental contamination. MPXV persistence increased with decreasing temperature. Additionally, we were able to show that MPXV could efficiently be inactivated by alcohol- and aldehyde-based surface disinfectants. These findings underline the stability of MPXV on inanimate surfaces and support the recommendations to use alcohol-based disinfectants as prevention measures or in outbreak situations.

摘要

非人畜共患猴痘病毒 (MPXV) 的传播需要重新评估卫生措施。迄今为止,有关 MPXV 表面稳定性的资料有限。在这里,我们评估了在不同温度下储存在不锈钢上的传染性 MPXV 的稳定性,同时使用不同的干扰物质来模拟环境污染。MPXV 的持久性随着温度的降低而增加。此外,我们能够表明,酒精和醛基表面消毒剂可以有效地使 MPXV 失活。这些发现强调了 MPXV 在无生命表面上的稳定性,并支持使用基于酒精的消毒剂作为预防措施或在暴发情况下的建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f747/10629702/0c2153317234/jiad127f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f747/10629702/692cd38e5bd8/jiad127f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f747/10629702/0c2153317234/jiad127f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f747/10629702/692cd38e5bd8/jiad127f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f747/10629702/0c2153317234/jiad127f2.jpg

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Emerg Infect Dis. 2023 Jan;29(1):189-192. doi: 10.3201/eid2901.221429. Epub 2022 Nov 17.
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