Chappell J E, Clandinin M T, Kearney-Volpe C
Am J Clin Nutr. 1985 Jul;42(1):49-56. doi: 10.1093/ajcn/42.1.49.
Geometric and positional isomers of octadecanoic acid in milk expressed during the first 9 weeks of lactation were determined for mothers delivering prematurely (PT) and at term (FT). Total C18:1 concentration was lower in PT than FT milk. C18:1 trans (elaidic acid) content was higher in PT and FT colostrum compared with subsequent milk samples. No relationship was observed between C18:1 trans level in milk and oleic acid, linoleic acid, total fatty acid levels, or volume of milk expressed. While gestational age and lactational stage appeared to affect the trans fatty acid pattern, the overriding influence was rate of maternal postpartum weight loss. Effect of weight loss on milk trans fatty acid levels was independent of maternal diet. Trans fatty acid content of milk as a function of recent maternal fat intake was also demonstrated. This study indicates that infants receiving human milk ingest levels of trans fatty acids reflecting short and long term maternal diet.
对早产（PT）和足月分娩（FT）的母亲在哺乳期前9周分泌的乳汁中十八烷酸的几何异构体和位置异构体进行了测定。PT组乳汁中总C18:1浓度低于FT组。与后续乳汁样本相比，PT组和FT组初乳中C18:1反式（反油酸）含量更高。未观察到乳汁中C18:1反式水平与油酸、亚油酸、总脂肪酸水平或乳汁分泌量之间存在关联。虽然胎龄和泌乳阶段似乎会影响反式脂肪酸模式，但最主要的影响因素是母亲产后体重减轻的速度。体重减轻对乳汁反式脂肪酸水平的影响与母亲饮食无关。还证明了乳汁反式脂肪酸含量与近期母亲脂肪摄入量的关系。这项研究表明，食用母乳的婴儿摄入的反式脂肪酸水平反映了母亲的短期和长期饮食情况。
