Elshewey Ahmed M, Selem Enas, Abed Amira Hassan
Department of Computer Science, Faculty of Computers and Information, Suez University, P.O.BOX:43221, Suez, Egypt.
Department of Information Technology, Faculty of Computers and Information, Suez University, P.O.BOX:43221, Suez, Egypt.
Sci Rep. 2025 May 22;15(1):17861. doi: 10.1038/s41598-025-02355-7.
Chronic kidney disease is a persistent ailment marked by the gradual decline of kidney function. Its classification primarily relies on the estimated glomerular filtration rate and the existence of kidney damage. The kidney disease improving global outcomes organization has established a widely accepted system for categorizing chronic kidney disease. explainable artificial intelligence for classification involves creating machine learning models that not only accurately predict outcomes but also offer clear and interpretable explanations for their decisions. Traditional machine learning models often pose difficulties in comprehending the intricate processes behind specific classification choices due to their intricate and obscure nature. In this study, an explainable artificial intelligence-chronic kidney disease model is introduced for the process of classification. The model applies explainable artificial intelligence by utilizing extra trees and shapley additive explanations values. Also, binary breadth-first search algorithm is used to select the most important features for the proposed explainable artificial intelligence-chronic kidney disease model. This methodology is designed to derive valuable insights for enhancing decision-making strategies within the field of classifying chronic kidney diseases. The performance of the proposed model is compared with another machine learning models, namely, random forest, decision tree, bagging classifier, adaptive boosting, and k-nearest neighbor, and the performance of the models is evaluated using accuracy, sensitivity, specificity, F-score, and area under the ROC curve. The experimental results demonstrated that the proposed model achieved the best results with accuracy equals 99.9%.
慢性肾脏病是一种以肾功能逐渐衰退为特征的持续性疾病。其分类主要依据估计的肾小球滤过率和肾脏损伤的存在情况。改善全球肾脏病预后组织已经建立了一个被广泛接受的慢性肾脏病分类系统。用于分类的可解释人工智能涉及创建机器学习模型,这些模型不仅能准确预测结果,还能为其决策提供清晰且可解释的说明。传统机器学习模型由于其复杂且晦涩的性质,在理解特定分类选择背后的复杂过程时往往存在困难。在本研究中,引入了一种用于分类过程的可解释人工智能 - 慢性肾脏病模型。该模型通过利用极端随机树和夏普利值来应用可解释人工智能。此外,使用二叉广度优先搜索算法为所提出的可解释人工智能 - 慢性肾脏病模型选择最重要的特征。此方法旨在为加强慢性肾脏病分类领域的决策策略得出有价值的见解。将所提出模型的性能与其他机器学习模型(即随机森林、决策树、装袋分类器、自适应提升和k近邻)进行比较,并使用准确率、灵敏度、特异性、F分数和ROC曲线下面积来评估模型的性能。实验结果表明,所提出的模型取得了最佳结果,准确率达到99.9%。