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来自结核分枝杆菌的核糖核酸制剂对小鼠麻风分枝杆菌感染缺乏保护作用。

Lack of protection afforded by ribonucleic acid preparations from Mycobacterium tuberculosis against Mycobacterium leprae infections in mice.

作者信息

Shepard C C, Youmans A Y, Youmans G P

出版信息

Infect Immun. 1977 Mar;15(3):733-6. doi: 10.1128/iai.15.3.733-736.1977.

Abstract

Mycobacterial ribonucleic acid preparations from H37Ra, an attenuated strain of Mycobacterium tuberculosis, provide their usual marked protection against M. tuberculosis challenge; however, they provided no protection against Mycobacterium leprae challenge. Suspensions of intact H37Ra were not effective against M. leprae. Suspensions of BCG gave their usual distinct protection against M. leprae challenge.

摘要

来自结核分枝杆菌减毒株H37Ra的分枝杆菌核糖核酸制剂,对结核分枝杆菌攻击能提供其通常显著的保护作用;然而,它们对麻风分枝杆菌攻击却没有提供保护。完整的H37Ra悬液对麻风分枝杆菌无效。卡介苗悬液对麻风分枝杆菌攻击给予其通常明显的保护作用。

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