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阿尔茨海默病中的空话及流畅性失语

Empty speech in Alzheimer's disease and fluent aphasia.

作者信息

Nicholas M, Obler L K, Albert M L, Helm-Estabrooks N

出版信息

J Speech Hear Res. 1985 Sep;28(3):405-10. doi: 10.1044/jshr.2803.405.

Abstract

Fourteen measures of empty speech during a picture description task were examined in four subject groups--patients with Alzheimer's dementia, Wernicke's aphasias, anomic aphasias, and normal controls--to discover if these groups could be distinguished on the basis of their discourse. Patients with Alzheimer's dementia were distinguished from patients with Wernicke's aphasia by producing more empty phrases and conjunctions, whereas patients with Wernicke's aphasia produced more neologisms, and verbal and literal paraphasias. The demented patients shared many empty speech characteristics with patients with anomic aphasia. Naming deficits, as measured by confrontation naming tasks, did not correlate with empty discourse production. Our findings may be useful clinically for distinguishing these different patient groups.

摘要

在一项图片描述任务中,对四个受试者组——阿尔茨海默病痴呆患者、韦尼克失语症患者、命名性失语症患者和正常对照组——的14种空洞言语指标进行了检查,以确定这些组是否可以根据其话语进行区分。阿尔茨海默病痴呆患者与韦尼克失语症患者的区别在于产生更多的空洞短语和连词,而韦尼克失语症患者产生更多的新造词、言语性错语和文字性错语。痴呆患者与命名性失语症患者有许多空洞言语特征。通过对命名任务的测量,命名缺陷与空洞话语的产生没有相关性。我们的研究结果在临床上可能有助于区分这些不同的患者组。

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