Jamil Rabia, Mughal Saba, Sohail Saba, Hossain Nazli
Rabia Jamil, MBBS, FCPS. Senior Registrar, Department of Obs & Gynae Unit-I, Civil Hospital Karachi (CHK)/Dow Medical College (DMC), Karachi, Pakistan.
Saba Mughal Lecturer, School of Public Health, Dow University of Health Sciences, Karachi.
Pak J Med Sci. 2025 May;41(5):1423-1428. doi: 10.12669/pjms.41.5.11529.
To assess the Effects of Ramadan fasting during third trimester on Doppler indices, non-stress test and perinatal outcomes.
This prospective, cross-sectional research was carried out in the Department of Obstetrics and Gynaecology unit 1, Dr Ruth KM Pfau Civil Hospital Karachi from March 2024 to May 2024. The study involved 100 participants they were divided into two groups, fasting group with minimum 10 days of fasting (Group-I) and non-fasting group (Group-II). Umbilical artery systolic/diastolic ratio, pulsatility index, middle cerebral artery pulsatility index and amniotic fluid index was measured during third trimester. This was followed by for non-stress test (cardiotocography) for about 30 minutes. Both groups were followed till delivery. At delivery placental weight, baby birth weight, head circumference, length and mid arm circumference of baby were recorded.
A total of 100 pregnant women were included. 52% (n=26) observed continuous fasting and 48% (n=24) observed intermittent fasting. Overall median age and BMI of pregnant women were 27 (IQR: 23-30) years and 25 (IQR: 24-29) kg/m, respectively. Amniotic fluid index was a bit higher in women who were not fasting (Median: 13.7, IQR: 11.0-15.0) as compared to those who fasted during pregnancy (Median: 12.3, IQR: 10.7-15.0). Although Doppler assessment and CTG findings did not show any significant association with the fasting status of pregnant women except median pulsatility index which was significantly higher in non-fasted group (1.0, IQR: 0.9-1.4 vs. 0.9, IQR: 0.7-1.1, p-value=0.002). Overall median weight of baby and Apgar score at 5-min were 3.0 (IQR: 2.8-3.2) kg and 8 (IQR: 8-10), respectively. The anthropometric measurements were similar in both groups.
Maternal fasting during Ramadan does not adversely affect Doppler indices, amniotic fluid index, non-stress test and fetal condition.
评估妊娠晚期斋月禁食对多普勒指数、无应激试验和围产期结局的影响。
这项前瞻性横断面研究于2024年3月至2024年5月在卡拉奇鲁思·KM·普法乌公民医院妇产科1单元进行。该研究纳入了100名参与者，他们被分为两组，禁食组（至少禁食10天，第一组）和非禁食组（第二组）。在妊娠晚期测量脐动脉收缩/舒张比、搏动指数、大脑中动脉搏动指数和羊水指数。随后进行约30分钟的无应激试验（胎心监护）。两组均随访至分娩。分娩时记录胎盘重量、婴儿出生体重、头围、身长和上臂围。
共纳入100名孕妇。52%（n = 26）的孕妇持续禁食，48%（n = 24）的孕妇间歇性禁食。孕妇的总体中位年龄和BMI分别为27（四分位间距：23 - 30）岁和25（四分位间距：24 - 29）kg/m²。与孕期禁食的女性相比，未禁食女性的羊水指数略高（中位数：13.7，四分位间距：11.0 - 15.0）（中位数：12.3，四分位间距：10.7 - 15.0）。尽管除了非禁食组的中位搏动指数显著较高外（1.0，四分位间距：0.9 - 1.4 vs. 0.9，四分位间距：0.7 - 1.1，p值 = 0.002），多普勒评估和胎心监护结果与孕妇的禁食状态没有显示出任何显著关联。婴儿的总体中位体重和5分钟时的阿氏评分分别为3.0（四分位间距：2.8 - 3.2）kg和8（四分位间距：8 - 10）。两组的人体测量指标相似。
斋月期间孕妇禁食不会对多普勒指数、羊水指数、无应激试验和胎儿状况产生不利影响。
