Gujarathi Akanksha M, Shah Preetam, Chaudhary Shweta, Lakade Laxmi, Davalbhakta Rucha, Patil Smita
Department of Pediatric and Preventive Dentistry, Bharati Vidyapeeth Dental College and Hospital, Pune, Maharashtra, India.
Int J Clin Pediatr Dent. 2025 Apr;18(4):412-419. doi: 10.5005/jp-journals-10005-3112. Epub 2025 May 19.
Dental caries is one of the most prevalent chronic infectious diseases, with its incidence increasing significantly over time. The global prevalence rate of dental caries in primary teeth stands at approximately 46.2% (Furiga et al.). To combat this widespread issue, remineralizing agents play a crucial role in reducing the prevalence rate, helping to restore and strengthen the demineralized tooth surface.
The aim of this study is to formulate the grape seed extract (GSE)-containing tooth mousse and to compare the remineralizing property with commercially available GC Tooth Mousse.
The remineralizing property of a formulated GSE-containing tooth mousse was compared with the gold standard GC Tooth Mousse by checking the microhardness values in extracted teeth samples divided into two groups: group A, treated with the GSE-containing tooth mousse, and group B, treated with the standardized GC Tooth Mousse.
There was a significant difference in microhardness between the baseline and after remineralization within each group. In the intergroup comparison after remineralization, the microhardness of group A was significantly greater than that of group B.
Both the commercially available GC Tooth Mousse and the formulated GSE-containing tooth mousse demonstrated good remineralizing potential, with the GSE-containing tooth mousse showing slightly better remineralizing potential compared to the commercially available GC Tooth Mousse.
Gujarathi AM, Shah P, Chaudhary S, . Formulation of Tooth Mousse Containing Grape Seed Extract and Comparative Evaluation of Its Remineralizing Effect with GC Tooth Mousse: An Study. Int J Clin Pediatr Dent 2025;18(4):412-419.
龋齿是最常见的慢性传染病之一,其发病率随时间显著上升。乳牙的全球龋齿患病率约为46.2%(弗里加等人)。为应对这一普遍问题,再矿化剂在降低患病率方面发挥着关键作用,有助于修复和强化脱矿的牙表面。
本研究旨在配制含葡萄籽提取物(GSE)的护齿泡沫,并与市售的GC护齿泡沫的再矿化性能进行比较。
通过检查分为两组的拔牙样本的显微硬度值,将配制的含GSE护齿泡沫的再矿化性能与金标准GC护齿泡沫进行比较:A组用含GSE护齿泡沫处理,B组用标准化GC护齿泡沫处理。
每组内基线和再矿化后的显微硬度有显著差异。再矿化后的组间比较中,A组的显微硬度显著高于B组。
市售的GC护齿泡沫和配制的含GSE护齿泡沫均显示出良好的再矿化潜力,含GSE护齿泡沫的再矿化潜力略优于市售的GC护齿泡沫。
古贾拉蒂AM,沙阿P,乔杜里S, 。含葡萄籽提取物护齿泡沫的配制及其与GC护齿泡沫再矿化效果的比较评价:一项 研究。《国际临床儿科牙科学杂志》2025;18(4):412 - 419。