用微球法测量氙气吸入期间的脑血流量。

Measurement of cerebral blood flow during xenon inhalation as measured by the microspheres method.

作者信息

Gur D, Yonas H, Jackson D L, Wolfson S K, Rockette H, Good W F, Maitz G S, Cook E E, Arena V C

出版信息

Stroke. 1985 Sep-Oct;16(5):871-4. doi: 10.1161/01.str.16.5.871.

DOI:10.1161/01.str.16.5.871

Abstract

Measurements of cerebral blood flow (CBF) were performed using the microsphere technique in non-human primates (baboons) to assess the effect of non-radioactive xenon gas inhalation on CBF. Blood flows in small tissue volumes (approximately 1 cm3) were directly measured before and during the inhalation of xenon/oxygen gas mixtures. The results of these studies demonstrated that when inhaled in relatively high concentrations, xenon gas does increase CBF, but the changes are more global than tissue-specific. The problems and limitations of such evaluations are discussed.

摘要

在非人类灵长类动物（狒狒）中使用微球技术测量脑血流量（CBF），以评估吸入非放射性氙气对CBF的影响。在吸入氙气/氧气混合气体之前和期间，直接测量小组织体积（约1立方厘米）中的血流量。这些研究结果表明，当以相对高的浓度吸入时，氙气确实会增加CBF，但这种变化更具全局性而非组织特异性。讨论了此类评估的问题和局限性。