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大鼠肢体撕脱伤和挤压伤中的动脉内膜损伤

Arterial intimal damage in avulsion and crush injuries in rat limbs.

作者信息

Glover M G, Seaber A V, Urbaniak J R

出版信息

J Reconstr Microsurg. 1985 Jul;1(4):247-51. doi: 10.1055/s-2007-1007082.

DOI:10.1055/s-2007-1007082
PMID:4057165
Abstract

A stereotypical pattern of arterial intimal damage has been demonstrated in rat avulsed and crushed injuries. These intimal tears can be found up to 6 cm proximal to the site of injury in avulsion injuries and are found at a delayed time with crush injuries. In both types of injury, circumferential intimal and subintimal tears spaced approximately 1 mm apart were demonstrated. These findings suggest a structural arrangement of the muscular artery wall that predisposes it to a reproducible pattern of damage. Veins undergoing the same avulsion and crushing procedure did not manifest any change. The presence of musculature rings or a weakened medial layer in artery walls after avulsion and crush injuries may influence short term patency and also long-term clinical replantation results.

摘要

在大鼠撕脱伤和挤压伤中已证实存在一种典型的动脉内膜损伤模式。在撕脱伤中,这些内膜撕裂可在距损伤部位近端达6厘米处发现,而在挤压伤中则在延迟时间出现。在这两种损伤类型中,均发现了间隔约1毫米的环形内膜和内膜下撕裂。这些发现提示了肌性动脉壁的一种结构排列,使其易于出现可重复的损伤模式。经历相同撕脱和挤压过程的静脉未表现出任何变化。撕脱伤和挤压伤后动脉壁中肌肉环的存在或中层的减弱可能会影响短期通畅性以及长期临床再植结果。

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1
Arterial intimal damage in avulsion and crush injuries in rat limbs.大鼠肢体撕脱伤和挤压伤中的动脉内膜损伤
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