Wang Yanhao
Department of Pediatrics, College of Chinese Medicine, Changchun University of Chinese Medicine, Changchun,130000, China.
Bioimpacts. 2025 Apr 6;15:30945. doi: 10.34172/bi.30945. eCollection 2025.
Numerous researchers have examined the environmental and regional characteristics, as well as the mother's dwelling air quality during pregnancy, that influence children's lung disease. The most common type of medicine is Western medicine, however Chinese medicine is more effective at treating lung conditions in youngsters. The common cold, pneumonia, bronchitis, asthma, chronic obstructive pulmonary disease (COPD), and lung cancer are among the respiratory ailments that traditional Chinese medicine (TCM) is frequently used to treat. TCM has qualities like resolving a variety of issues, focusing on several areas, and reducing harmful side effects. TCM has justified its anti-asthma, bronchiolitis, and pulmonary fibrosis (PF) effect in clinical practice but its underlying mechanism and specific role in mentioned disease are still unknown. According to some animal research, the traditional recipe, precise measurements, and organic substances extracted from TCM could considerably reduce changes in the structure of the airways and show anti-inflammatory properties. By examining these results and information, we will talk about the potential Patho mechanism that underlies asthmatic airway inflammation and remodeling as well as the special function of TCM in asthma treatment by controlling various signaling pathways. We provide a summary of the developments in research on TCM extracts for the treatment of asthma, bronchiolitis, PF, and lung cancer in this review paper. Additionally, we shall discuss a few cellular aspects.
众多研究人员已考察了影响儿童肺部疾病的环境和区域特征,以及母亲孕期的居住空气质量。最常见的药物类型是西药,然而中药在治疗儿童肺部疾病方面更有效。普通感冒、肺炎、支气管炎、哮喘、慢性阻塞性肺疾病(COPD)和肺癌等都是常用中医(TCM)治疗的呼吸道疾病。中医具有解决多种问题、关注多个方面以及减少有害副作用等特点。中医在临床实践中已证明其对哮喘、细支气管炎和肺纤维化(PF)有疗效,但其潜在机制以及在上述疾病中的具体作用仍不明确。根据一些动物研究,中医的传统配方、精确剂量和提取的有机物质可显著减少气道结构变化并显示出抗炎特性。通过审视这些结果和信息,我们将探讨哮喘气道炎症和重塑潜在的病理机制,以及中医通过控制各种信号通路在哮喘治疗中的特殊作用。在这篇综述论文中,我们总结了中医提取物治疗哮喘、细支气管炎、PF和肺癌的研究进展。此外,我们还将讨论一些细胞层面的内容。