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双焦点隐形眼镜与离焦软镜对低散光近视患者近视控制的比较有效性:一项回顾性研究

Comparative effectiveness of dual-focus contact lenses and DIMS spectacle lenses for myopia control in patients with low astigmatism: a retrospective study.

作者信息

Lee Chia-Yi, Yang Shun-Fa, Chang Yu-Ling, Huang Jing-Yang, Lian Ie-Bin, Chang Chao-Kai

机构信息

Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.

Nobel Eye Institute, Taipei, Taiwan.

出版信息

Front Med (Lausanne). 2025 Jun 18;12:1524700. doi: 10.3389/fmed.2025.1524700. eCollection 2025.

Abstract

PURPOSE

This study aimed to evaluate and compare the effectiveness of dual-focus contact lenses (DFCL) and defocus incorporated multiple segment (DIMS) spectacle lenses in controlling myopia progression in patients with low astigmatism.

METHODS

A retrospective cohort study was conducted involving myopic patients with astigmatism of less than -1.25 diopters (D) who used either DFCL or DIMS spectacle lenses. The study included 95 eyes in the DFCL group and 88 eyes in the DIMS group, and the spherical equivalent refraction (SER) of the study population ranged from -0.50 D to -6.00 D. The primary outcomes were the progression of SER and the elongation of axial length (AXL) over 1 year. A generalized linear mixed model was used to calculate adjusted odds ratios (aORs) and the associated 95% confidence intervals (CIs), adjusting for age, sex, initial AXL, and initial SER.

RESULTS

The mean SER progression was -0.28 ± 0.15 D in the DFCL group and -0.25 ± 0.12 D in the DIMS group ( = 0.139). The mean AXL elongation was 0.12 ± 0.07 mm for DFCL users and 0.10 ± 0.05 mm for DIMS users ( = 0.029). Trend analysis revealed no significant differences in SER progression (aOR: 0.988; 95% CI: 0.945-1.033;  = 0.513) or AXL elongation (aOR: 0.982; 95% CI: 0.945-1.018;  = 0.307) between the groups after adjusting for confounders. Subgroup analyses indicated no significant differences in SER progression or AXL elongation between DIMS and DFCL users across different baseline characteristics (all  > 0.05).

CONCLUSION

The use of DIMS spectacle lenses showed SER and AXL control similar to that of DFCL.

摘要

目的

本研究旨在评估和比较双焦点隐形眼镜(DFCL)和离焦整合多焦点(DIMS)框架眼镜在控制低散光患者近视进展方面的有效性。

方法

进行了一项回顾性队列研究,纳入散光低于-1.25屈光度(D)的近视患者,他们使用DFCL或DIMS框架眼镜。研究包括DFCL组的95只眼和DIMS组的88只眼,研究人群的等效球镜度(SER)范围为-0.50 D至-6.00 D。主要结局是1年内SER的进展和眼轴长度(AXL)的延长。使用广义线性混合模型计算调整后的优势比(aOR)和相关的95%置信区间(CI),并对年龄、性别、初始AXL和初始SER进行校正。

结果

DFCL组的平均SER进展为-0.28±0.15 D,DIMS组为-0.25±0.12 D(P=0.139)。DFCL使用者的平均AXL延长为0.12±0.07 mm,DIMS使用者为0.10±0.05 mm(P=0.029)。趋势分析显示,校正混杂因素后,两组之间在SER进展(aOR:0.988;95%CI:0.945-1.033;P=0.513)或AXL延长(aOR:0.982;95%CI:0.945-1.018;P=0.307)方面无显著差异。亚组分析表明,在不同基线特征的DIMS和DFCL使用者之间,SER进展或AXL延长均无显著差异(均P>0.05)。

结论

使用DIMS框架眼镜显示出与DFCL相似的SER和AXL控制效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b90c/12213690/11c7e9c0f66e/fmed-12-1524700-g001.jpg

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