Cruz-Estupiñan Sharon Elizabeth, Higuera-Piedrahita Rosa Isabel, Bulla-Castañeda Diana María, Ballesteros-Ricaurte Javier Antonio, Pulido-Medellin Martin Orlando
Grupo de Investigación en Medicina Veterinaria y Zootecnia (GIDIMEVETZ), Universidad Pedagógica y Tecnológica de Colombia, Tunja, Colombia.
Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli, Mexico.
J Parasitol Res. 2025 Jul 1;2025:9987439. doi: 10.1155/japr/9987439. eCollection 2025.
The genus , belonging to the family Asteraceae, comprises nearly 500 species with various pharmacological properties, such as antimalarial, antibacterial, antifungal, antioxidant, nematocidal, and cesticidal activities. Gastrointestinal parasites pose a significant health concern in animals, resulting in substantial financial losses due to the ineffectiveness of current prevention and control measures, further compounded by the rise of antiparasitic resistance. Consequently, there has been a surge in research endeavors aimed at identifying sustainable alternatives to address this issue, with a particular focus on herbalism due to its promise in this field. has been identified as a source of secondary metabolites with the potential to kill parasites, making it a promising natural alternative to synthetic drugs. The objective of this article is to provide a comprehensive review of the genus and its application in the control of gastrointestinal parasites. A comprehensive search was conducted using multiple databases, including Springer, Science Direct, Scopus, Web of Science, Latindex, PubMed, and SciELo, with specific keywords such as ", Artemisin, gastrointestinal parasites, effect, resistance". After a thorough review of the literature, 15 articles were identified as meeting the selection criteria. These articles encompassed studies on plants from the genus , exploring their response to parasites in both free and endogenous life stages. Additionally, the review included studies on molecules derived from plants in the genus , their ethnobotanical applications in addressing parasites, and their ethnoveterinary uses. These studies demonstrated that , whether in vivo or in vitro, exhibited an impact on various gastrointestinal parasites and yielded positive or negative outcomes in the treatment of different parasite species.
该属属于菊科，包含近500个物种，具有多种药理特性，如抗疟疾、抗菌、抗真菌、抗氧化、杀线虫和杀绦虫活性。胃肠道寄生虫对动物健康构成重大威胁，由于当前预防和控制措施无效，导致巨大的经济损失，而抗寄生虫耐药性的上升使情况更加复杂。因此，旨在寻找可持续替代方案来解决这一问题的研究工作激增，由于草药医学在该领域的前景，人们尤其关注它。已被确定为具有杀死寄生虫潜力的次生代谢物来源，使其成为合成药物有前景的天然替代品。本文的目的是对该属及其在控制胃肠道寄生虫方面的应用进行全面综述。使用多个数据库进行了全面搜索，包括施普林格、科学Direct、Scopus、科学网、拉丁索引、PubMed和SciELO，使用了特定关键词，如“，青蒿素，胃肠道寄生虫，作用，耐药性”。在对文献进行全面审查后，确定有15篇文章符合选择标准。这些文章包括对该属植物的研究，探讨它们在自由生活和内生生活阶段对寄生虫的反应。此外，综述还包括对该属植物衍生分子的研究、它们在解决寄生虫问题方面的民族植物学应用以及它们的民族兽医学用途。这些研究表明，无论在体内还是体外，对各种胃肠道寄生虫都有影响，并且在治疗不同寄生虫物种时产生了积极或消极的结果。
