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糖尿病发病率和护理质量方面的社会不平等:意大利拉齐奥地区一项队列研究的结果

Social inequalities in diabetes incidence and quality of care: results from a cohort study in the Lazio region, Italy.

作者信息

Nardi Angelo, Sorge Chiara, Cascini Silvia, Davoli Marina, Agabiti Nera, Dalla Zuanna Teresa, Cesaroni Giulia

机构信息

Health District 2, Local Health Authority Rome 1, Rome, Italy

Department of Epidemiology-Regional Health Service, Local Health Authority Rome 1, Rome, Italy.

出版信息

BMJ Open. 2025 Jul 17;15(7):e091738. doi: 10.1136/bmjopen-2024-091738.

Abstract

OBJECTIVES

Socioeconomic disparities in diabetes incidence vary across countries and geographical areas. In addition, once diabetes is diagnosed, further disparities can arise during the whole care process. This study aims to evaluate disparities in incidence and glycated haemoglobin (HbA1c) testing in Central Italy.

DESIGN

Cohort study.

SETTING

Lazio region, Italy.

PARTICIPANTS

We used the Lazio Region Longitudinal Study, which is the 2011 census cohort of all residents followed from January 2012 to December 2022. We selected 2 912 539 diabetes-free individuals aged 35-90 years at baseline (54% women). We used educational attainment as the indicator of socioeconomic position and place of residence and birth citizenship as possible confounders.

MAIN OUTCOME MEASURES

We identified incident cases of type 2 diabetes from 2012 to 2022 using health databases. We searched for an HbA1c test in the 13 months following case identification. We used Cox proportional hazard models and logistic regression models stratified by sex to study disparities in diabetes incidence and HbA1c testing, respectively.

RESULTS

We identified 192 268 new cases (49% women). We found incidence disparities, with the lowest educational level showing a risk that is twice or more than the highest in men (HR 2.03, 95% CI 1.98 to 2.08) and women (HR 2.32, 95% CI 2.26 to 2.39), respectively. Disparities were less pronounced in the older groups. Fewer than 60% of individuals across all educational levels had at least one HbA1c test. Compared with those with university degrees, people with the lowest education showed a higher probability of being tested for HbA1c in men (OR 1.56, 95% CI 1.48 to 1.64) and women (OR 1.62, 95% CI 1.53 to 1.72).

CONCLUSIONS

We found inequalities in diabetes incidence in both sexes, mainly among younger groups. The highly educated were less likely to be tested for HbA1c, although different private sector utilisation could have influenced this result.

摘要

目的

糖尿病发病率的社会经济差异在不同国家和地理区域有所不同。此外,一旦确诊糖尿病,在整个护理过程中可能会出现进一步的差异。本研究旨在评估意大利中部地区糖尿病发病率和糖化血红蛋白(HbA1c)检测方面的差异。

设计

队列研究。

背景

意大利拉齐奥地区。

参与者

我们使用了拉齐奥地区纵向研究,该研究是对2011年人口普查中所有居民进行的队列研究,从2012年1月持续到2022年12月。我们选择了2912539名基线时年龄在35 - 90岁的无糖尿病个体(女性占54%)。我们将受教育程度作为社会经济地位的指标,并将居住地点和出生公民身份作为可能的混杂因素。

主要观察指标

我们使用健康数据库确定2012年至2022年期间2型糖尿病的新发病例。在病例确诊后的13个月内搜索HbA1c检测记录。我们分别使用按性别分层的Cox比例风险模型和逻辑回归模型来研究糖尿病发病率和HbA1c检测方面的差异。

结果

我们确定了192268例新病例(女性占49%)。我们发现了发病率差异,男性中受教育程度最低者的患病风险是最高者的两倍或更高(风险比[HR] 2.03,95%置信区间[CI] 1.98至2.08),女性中这一比例为2.32(95% CI 2.26至2.39)。年龄较大的组中差异不太明显。所有教育水平中,不到60%的个体至少进行过一次HbA1c检测。与拥有大学学位的人相比,受教育程度最低的男性进行HbA1c检测的可能性更高(优势比[OR] 1.56,95% CI 1.48至1.64),女性为1.62(95% CI 1.53至1.72)。

结论

我们发现两性在糖尿病发病率方面存在不平等,主要集中在较年轻的群体中。受过高等教育的人进行HbA1c检测的可能性较低,尽管不同的私营部门利用情况可能影响了这一结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57d3/12273125/817e1d2d90ca/bmjopen-15-7-g001.jpg

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