Sertbaş Meltem, Özaydin Özlem, Yilmaz Habip, Güner Abdullah Emre, Güdük Özden, Okuroğlu Nalan, Özdemir Ali, Sertbaş Yaşar
Department of Internal Medicine, Fatih Sultan Mehmet Training and Research Hospital, Health Sciences University, İstanbul, Turkiye.
Türkiye Institute of Health Policies, TÜSEB, İstanbul, Turkiye.
Turk J Med Sci. 2025 Mar 26;55(3):559-571. doi: 10.55730/1300-0144.6003. eCollection 2025.
BACKGROUND/AIM: The study aims to systematically analyze the body of literature concerning the effects of colchicine on the cardiovascular system, providing a comprehensive evaluation of the current knowledge and highlighting the clinical and scientific relevance of colchicine in this field.
Data were obtained from the Web of Science (WOS), Scopus, and PubMed databases on March 17, 2025. The search terms included "Colchicine" AND ("Cardiovascular Diseases" OR "Heart Diseases" OR "Coronary Artery Disease" OR "Myocarditis" OR "Pericarditis" OR "Atherosclerosis" OR "Heart Failure" OR "Myocardial Infarction" OR "Ischemic Heart Disease" OR "Acute Coronary Syndrome" OR "Cardiac Arrhythmias" OR "Thrombosis" OR "Stroke"). No restrictions were applied regarding publication date or language, ensuring the comprehensive retrieval of relevant data. Publications were categorized according to their document type and indexes. Additionally, a cooccurrence analysis of key words was conducted using VOSviewer 1.6.18.
A total of 425 publications on the effects of colchicine on the cardiovascular system were identified, published between 1976 and 2025. There has been a significant increase in research since 2015. Most publications were in the Cardiac Cardiovascular Systems category. "Colchicine" was the most frequently used key word, appearing 170 times. The USA ranked first in publication count, with 163 studies. The USA, Italy, Canada, and China played significant roles in global research collaboration.
This bibliometric analysis demonstrates the increasing importance of colchicine as a therapeutic agent in the management of cardiovascular disease.
背景/目的：本研究旨在系统分析有关秋水仙碱对心血管系统影响的文献，全面评估现有知识，并突出秋水仙碱在该领域的临床和科学相关性。
于2025年3月17日从科学网（WOS）、Scopus和PubMed数据库获取数据。检索词包括“秋水仙碱”以及（“心血管疾病”或“心脏病”或“冠状动脉疾病”或“心肌炎”或“心包炎”或“动脉粥样硬化”或“心力衰竭”或“心肌梗死”或“缺血性心脏病”或“急性冠状动脉综合征”或“心律失常”或“血栓形成”或“中风”）。对出版日期或语言不设限制，以确保全面检索相关数据。出版物根据其文献类型和索引进行分类。此外，使用VOSviewer 1.6.18对关键词进行共现分析。
共识别出425篇关于秋水仙碱对心血管系统影响的出版物，发表时间为1976年至2025年。自2015年以来研究显著增加。大多数出版物属于心血管系统类别。“秋水仙碱”是最常用的关键词，出现170次。美国的出版物数量排名第一，有163项研究。美国、意大利、加拿大和中国在全球研究合作中发挥了重要作用。
这项文献计量分析表明秋水仙碱作为心血管疾病治疗药物的重要性日益增加。
